Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis

KA Williams, YS Roh, I Brown, N Sutaria… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized by
intensely pruritic, hyperkeratotic nodules distributed on the trunk and extensor surfaces of …

[HTML][HTML] Trial of nemolizumab in moderate-to-severe prurigo nodularis

S Ständer, G Yosipovitch, FJ Legat… - … England Journal of …, 2020 - Mass Medical Soc
Background Prurigo nodularis is a chronic pruritic skin disease with multiple nodular skin
lesions. Nemolizumab is a monoclonal antibody targeting the interleukin-31 receptor, which …

Chronic prurigo

L Misery - British Journal of Dermatology, 2022 - academic.oup.com
Chronic prurigo is a distinct disease defined by the presence of chronic pruritus for at least 6
weeks, a history and/or signs of repeated scratching, and multiple localized or generalized …

[HTML][HTML] IFSI-guideline on chronic prurigo including prurigo nodularis

S Ständer, MP Pereira, T Berger, C Zeidler, M Augustin… - Itch, 2020 - journals.lww.com
Chronic prurigo (CPG) is a highly burdensome pruritic disease characterized by chronic itch,
a prolonged scratching behavior and the development of localized or generalized …

[HTML][HTML] Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double …

H Sofen, R Bissonnette, G Yosipovitch… - …, 2023 - thelancet.com
Background Prurigo nodularis is a chronic skin disease characterised by intensely pruritic,
hyperkeratotic nodules. Vixarelimab, a human monoclonal antibody, binds to the beta …

Chronic nodular prurigo: clinical profile and burden. A European cross‐sectional study

MP Pereira, V Hoffmann, E Weisshaar… - Journal of the …, 2020 - Wiley Online Library
Background Chronic nodular prurigo (CNPG) is a condition characterized by chronic itch, a
prolonged scratching behaviour and the presence of pruriginous nodules. A comprehensive …

Nemolizumab efficacy in prurigo nodularis: onset of action on itch and sleep disturbances

S Ständer, G Yosipovitch, JP Lacour… - Journal of the …, 2022 - Wiley Online Library
Background Patients with prurigo nodularis (PN) have multiple itchy nodules, impaired
quality of life and sleep deprivation. Prurigo nodularis patients have a high burden of …

Health-related quality of life and economic burden of prurigo nodularis

KA Whang, TK Le, R Khanna, KA Williams… - Journal of the American …, 2022 - Elsevier
Background Prurigo nodularis (PN) is an understudied, pruritic inflammatory skin disease.
Little is known about the effect of PN on quality of life and its associated economic burden …

A polygenic risk score for predicting racial and genetic susceptibility to prurigo nodularis

C Vasavda, G Wan, MD Szeto, M Marani… - Journal of Investigative …, 2023 - Elsevier
Prurigo nodularis (PN) is an understudied inflammatory skin disease characterized by
pruritic, hyperkeratotic nodules. Identifying the genetic factors underlying PN could help to …

[HTML][HTML] Itch and mental health in dermatological patients across Europe: a cross-sectional study in 13 countries

FJ Dalgard, Å Svensson, JA Halvorsen, U Gieler… - Journal of Investigative …, 2020 - Elsevier
Itch is a highly prevalent and multidimensional symptom. We aimed to analyze the
association between itch and mental health in dermatological patients. This multicenter …