Resveratrol prevents fibrosis, NF‐κB activation and TGF‐β increases induced by chronic CCl4 treatment in rats

E Chávez, K Reyes‐Gordillo, J Segovia… - Journal of Applied …, 2008 - Wiley Online Library
Resveratrol is a nonflavonoid polyphenol with antioxidant, anticancer and antiinflammatory
properties. Moreover, it has been reported that this compound inhibits NF‐κB, which …

Coffee attenuates fibrosis by decreasing the expression of TGF‐β and CTGF in a murine model of liver damage

J Arauz, MG Moreno, P Cortés‐Reynosa… - Journal of Applied …, 2013 - Wiley Online Library
This study was performed to evaluate the antifibrotic properties of coffee in a model of liver
damage induced by repeated administration of thioacetamide (TAA) in male Wistar rats. In …

Acute neuroinflammatory response in the substantia nigra pars compacta of rats after a local injection of lipopolysaccharide

YM Flores-Martinez… - Journal of …, 2018 - Wiley Online Library
Models of Parkinson's disease with neurotoxins have shown that microglial activation does
not evoke a typical inflammatory response in the substantia nigra, questioning whether …

Neurotensin polyplex as an efficient carrier for delivering the human GDNF gene into nigral dopamine neurons of hemiparkinsonian rats

JA Gonzalez-Barrios, M Lindahl, MJ Bannon… - Molecular Therapy, 2006 - cell.com
Recently we showed that the neurotensin polyplex is a nanoparticle carrier system that
targets reporter genes in nigral dopamine neurons in vivo. Herein, we report its first practical …

Caffeine prevents experimental liver fibrosis by blocking the expression of TGF-β

J Arauz, N Zarco, J Segovia, M Shibayama… - European journal of …, 2014 - journals.lww.com
Background There is a growing body of evidence that caffeine exerts beneficial effects on
the liver; however, the molecular mechanisms by which caffeine exerts beneficial effects on …

Hypothyroidism induces selective oxidative stress in amygdala and hippocampus of rat

E Cano-Europa, F Pérez-Severiano, P Vergara… - Metabolic Brain …, 2008 - Springer
The effects of hypothyroidism on lipid peroxidation (LP), reactive oxygen species (ROS), and
nitric oxide synthase (NOS), levels and expression, in rat brain were examined …

Dopamine abnormalities in the neocortex of patients with temporal lobe epilepsy

L Rocha, M Alonso-Vanegas, J Villeda-Hernández… - Neurobiology of …, 2012 - Elsevier
Experiments were designed to evaluate different variables of the dopaminergic system in the
temporal cortex of surgically treated patients with temporal lobe epilepsy (TLE) associated …

Dystrophin Dp71 isoforms are differentially expressed in the mouse brain and retina: report of new alternative splicing and a novel nomenclature for Dp71 isoforms

J Aragón, M González-Reyes, J Romo-Yáñez… - Molecular …, 2018 - Springer
Multiple dystrophin Dp71 isoforms have been identified in rats, mice, and humans and in
several cell line models. These Dp71 isoforms are produced by the alternative splicing of …

N-acetylcysteine prevents carbon tetrachloride-induced liver cirrhosis: role of liver transforming growth factor-beta and oxidative stress

M Galicia-Moreno, A Rodríguez-Rivera… - European journal of …, 2009 - journals.lww.com
Objectives N-acetylcysteine (NAC) is an antioxidant, a precursor of reduced glutathione, and
an inhibitor of the profibrotic cytokine liver transforming growth factor-beta (TGF-β). Carbon …

Nicotinic acid prevents experimental liver fibrosis by attenuating the prooxidant process

J Arauz, Y Rivera-Espinoza, M Shibayama… - International …, 2015 - Elsevier
Liver fibrosis is the excessive accumulation of extracellular matrix proteins that occurs in
most chronic liver diseases. Nicotinamide treatment has been shown to prevent collagen …