A perspective on how fibrinaloid microclots and platelet pathology may be applied in clinical investigations
E Pretorius, DB Kell - Seminars in Thrombosis and Hemostasis, 2023 - thieme-connect.com
Microscopy imaging has enabled us to establish the presence of fibrin (ogen) amyloid
(fibrinaloid) microclots in a range of chronic, inflammatory diseases. Microclots may also be …
(fibrinaloid) microclots in a range of chronic, inflammatory diseases. Microclots may also be …
[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries
DC Arhontoulis, CM Kerr, D Richards… - Journal of Tissue …, 2022 - Wiley Online Library
Acute cardiac injuries occur in 20%–25% of hospitalized COVID‐19 patients. Herein, we
demonstrate that human cardiac organoids (hCOs) are a viable platform to model the …
demonstrate that human cardiac organoids (hCOs) are a viable platform to model the …
Association of trauma molecular endotypes with differential response to transfusion resuscitation strategies
MR Thau, T Liu, NA Sathe, GE O'Keefe… - JAMA …, 2023 - jamanetwork.com
Importance It is not clear which severely injured patients with hemorrhagic shock may
benefit most from a 1: 1: 1 vs 1: 1: 2 (plasma: platelets: red blood cells) resuscitation strategy …
benefit most from a 1: 1: 1 vs 1: 1: 2 (plasma: platelets: red blood cells) resuscitation strategy …
RNF213-associated urticarial lesions with hypercytokinemia
C Louvrier, F Awad, A Cosnes, E El Khouri… - Journal of Allergy and …, 2022 - Elsevier
Background Urticarial lesions are observed in both cutaneous and systemic disorders.
Familial forms of urticarial syndromes are rare and can be encountered in systemic …
Familial forms of urticarial syndromes are rare and can be encountered in systemic …
COVID-19 severity shifts the cytokine milieu toward a proinflammatory state in Egyptian patients: a cross-sectional study
Despite extensive research to decipher the immunological basis of coronavirus disease
(COVID-19), limited evidence on immunological correlates of COVID-19 severity from MENA …
(COVID-19), limited evidence on immunological correlates of COVID-19 severity from MENA …
Differential absolute plasma IL-6 concentrations between two immunoassay platforms in intensive care unit patients with COVID-19
PK Bhatraju, ED Morrell, NG O'Connor… - Biomarkers in …, 2023 - Taylor & Francis
Objectives: Explore whether plasma IL-6 levels are similar across biomarker platforms and
association with COVID-19 clinical outcomes. Methods: Plasma IL-6 concentrations were …
association with COVID-19 clinical outcomes. Methods: Plasma IL-6 concentrations were …