Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

To our knowledge, no previous meta-analysis has attempted to compare the efficacy of
pharmacological, psychological and combined treatments for the three main anxiety …

Since Freud, clinicians have understood that disturbing memories contribute to
psychopathology and that new emotional experiences contribute to therapeutic change. Yet …

We conducted a meta-analysis of randomized trials in which the effects of treatment with
antidepressant medication were compared to the effects of combined pharmacotherapy and …

Although psychotherapy and antidepressant medication are efficacious in the treatment of
depressive and anxiety disorders, it is not known whether they are equally efficacious for all …

Objective: To provide practical clinical guidance for the treatment of adults with panic
disorder, social anxiety disorder and generalised anxiety disorder in Australia and New …

Objective: Understanding for whom, and under what conditions, treatments exert their
greatest effects is essential for developing personalized medicine. Research investigating …

Neuroticism--the tendency to experience negative emotions, along with the perception that
the world is filled with stressful, unmanageable challenges--is strongly associated with …

Posttraumatic stress disorder manifests after exposure to a traumatic event and is
characterized by avoidance/numbing, intrusive symptoms and flashbacks, mood and …

BackgroundPsychotherapies are the treatment of choice for panic disorder, but which should
be considered as first-line treatment is yet to be substantiated by evidence. AimsTo examine …