Topical and cutaneous delivery using nanosystems

MS Roberts, Y Mohammed, MN Pastore… - Journal of controlled …, 2017 - Elsevier
The goal of topical and cutaneous delivery is to deliver therapeutic and other substances to
a desired target site in the skin at appropriate doses to achieve a safe and efficacious …

Non-invasive drug delivery technology: Development and current status of transdermal drug delivery devices, techniques and biomedical applications

N Akhtar, V Singh, M Yusuf, RA Khan - Biomedical Engineering …, 2020 - degruyter.com
Pay-load deliveries across the skin barrier to the systemic circulation have been one of the
most challenging delivery options. Necessitated requirements of the skin and facilitated skin …

Nanoparticle-enabled transdermal drug delivery systems for enhanced dose control and tissue targeting

BC Palmer, LA DeLouise - Molecules, 2016 - mdpi.com
Transdermal drug delivery systems have been around for decades, and current
technologies (eg, patches, ointments, and creams) enhance the skin permeation of low …

Nanoparticles for topical drug delivery: Potential for skin cancer treatment

V Krishnan, S Mitragotri - Advanced Drug Delivery Reviews, 2020 - Elsevier
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …

Absorption, distribution, metabolism, and excretion of nanocarriers in vivo and their influences

A Zhang, K Meng, Y Liu, Y Pan, W Qu, D Chen… - Advances in Colloid and …, 2020 - Elsevier
As one of the most promising and effective delivery systems for targeted controlled-release
drugs, nanocarriers (NCs) have been widely studied. Although the development of …

In-vivo evaluation of Alginate-Pectin hydrogel film loaded with Simvastatin for diabetic wound healing in Streptozotocin-induced diabetic rats

M Rezvanian, SF Ng, T Alavi, W Ahmad - International Journal of Biological …, 2021 - Elsevier
Previously we developed and characterized a novel hydrogel film wound dressing
containing Sodium Alginate and Pectin loaded with Simvastatin with multi-functional …

Combinatorial lipid-nanosystem for dermal delivery of 5-fluorouracil and resveratrol against skin cancer: Delineation of improved dermatokinetics and epidermal drug …

MK Iqubal, A Iqubal, K Imtiyaz, MMA Rizvi… - European Journal of …, 2021 - Elsevier
In the present study, combinatorial nanostructured lipid carrier gel of 5-fluorouracil and
resveratrol was formulated, optimized and characterized to enhance permeation in between …

Natural polysaccharide-based biodegradable polymeric platforms for transdermal drug delivery system: A critical analysis

S Noreen, JX Ma, M Saeed, F Pervaiz, MF Hanif… - Drug Delivery and …, 2022 - Springer
Natural biodegradable polymers generally include polysaccharides (starch, alginate,
chitin/chitosan, hyaluronic acid derivatives, etc.) and proteins (collagen, gelatin, fibrin, etc.) …

Cetyltrimethylammonium bromide-nanocrystalline cellulose (CTAB-NCC) based microemulsions for enhancement of topical delivery of curcumin

N Zainuddin, I Ahmad, MH Zulfakar… - Carbohydrate …, 2021 - Elsevier
Low bioavailability and poor water solubility have limited the utilization of curcumin in
conventional dosing methods. As an alternative, microemulsions as drug carrier can …

[HTML][HTML] Overcoming drug delivery barriers and challenges in topical therapy of atopic dermatitis: A nanotechnological perspective

C Hemrajani, P Negi, A Parashar, G Gupta… - Biomedicine & …, 2022 - Elsevier
Atopic dermatitis (AD) is an inflammatory disorder centered around loss of epidermal barrier
function, and T helper 2 (Th2) immune responses. The current understanding of disease …