Development of β-cell mass in fetuses of rats deprived of protein and/or energy in last trimester of pregnancy

E Bertin, MN Gangnerau, G Bellon… - American Journal …, 2002 - journals.physiology.org
Fetal malnutrition is now proposed as a risk factor of later obesity and type II diabetes. We
previously analyzed the long-term impact of reduced protein and/or energy intake strictly …

Glucose metabolism and β-cell mass in adult offspring of rats protein and/or energy restricted during the last week of pregnancy

E Bertin, MN Gangnerau, D Bailbé… - American Journal of …, 1999 - journals.physiology.org
An association between low birth weight and later impaired glucose tolerance was recently
demonstrated in several human populations. Although fetal malnutrition is probably …

Impact of malnutrition on in-hospital outcomes in takotsubo cardiomyopathy

P Li, C Li, AK Mishra, P Cai, X Lu, AA Sherif, L Jin… - Nutrition, 2022 - Elsevier
Objective This study assesses the effect of malnutrition on the in-hospital outcomes of
patients with takotsubo cardiomyopathy (TCM). Methods We performed a retrospective …

Altered activity of the autonomous nervous system as a determinant of the impaired β-cell secretory response after protein-energy restriction in the rat

T Leon-Quinto, C Magnan, B Portha - Endocrinology, 1998 - academic.oup.com
Glucose-induced insulin secretion in vivo is known to be severely blunted in the rat as a
consequence of protein-energy restriction starting early in life. We have recently reported in …

Recurrent hypoglycemia is associated with loss of activation in rat brain cingulate cortex

P Hurst, AS Garfield, C Marrow, LK Heisler… - …, 2012 - academic.oup.com
A subset of people with diabetes fail to mount defensive counterregulatory responses (CRR)
to hypoglycemia. Although the mechanisms by which this occurs remain unclear, recurrent …

Energy restriction with protein restriction increases basal metabolism and meal-induced thermogenesis in rats

PC Even, E Bertin, MN Gangnerau… - American Journal …, 2003 - journals.physiology.org
We previously observed an increased sympathetic nervous system (SNS) activity that was
partly responsible for a defect in the insulin secretion response to glucose after postweaning …

Functional and structural adaptations in the pancreatic α-cell and changes in glucagon signaling during protein malnutrition

L Marroquí, TM Batista, A Gonzalez, E Vieira… - …, 2012 - academic.oup.com
Chronic malnutrition leads to multiple changes in β-cell function and peripheral insulin
actions to adapt glucose homeostasis to these restricted conditions. However, despite …

Sustained liver glucose release in response to adrenaline can improve hypoglycaemic episodes in rats under food restriction subjected to acute exercise

LKR Babata, MMD Pedrosa, RF Garcia… - International journal …, 2014 - Wiley Online Library
Background. As the liver is important for blood glucose regulation, this study aimed at
relating liver glucose release stimulated by glucagon and adrenaline to in vivo episodes of …

Mitogenic factors accelerate later-age diseases: insulin as a paradigm

A Lev-Ran - Mechanisms of ageing and development, 1998 - Elsevier
Some genes are expressed differently in earlier and later generations of most cell lines.
Many diseases become clinically expressed only later in life, and show clustering of the age …

Effect of early dietary restriction on insulin action and secretion in the GK rat, a spontaneous model of NIDDM

C Alvarez, D Bailbe… - American Journal …, 2000 - journals.physiology.org
The availability of the Goto-Kakisaki (GK) rat model of non-insulin-dependent diabetes
mellitus prompted us to test the effect of a limited period of undernutrition in previously …