The cytotoxic anti-cancer drugs cisplatin, paclitaxel, doxorubicin, 5-fluorouracil (5-FU), as
well as targeted drugs including imatinib, erlotinib, and nivolumab, play key roles in clinical …

Cell cycle is one of the main cellular mechanisms involved in tumor progression. Almost all
of the active molecular pathways in tumor cells directly or indirectly target the cell cycle …

Inflammation is a hallmark of cancer. In patients with cancer, peripheral blood myeloid
expansion, indicated by a high neutrophil-to-lymphocyte ratio, associates with shorter …

Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer with
exceedingly poor prognosis, and chemoresistance is a huge challenge for treatment. N6 …

Primordial follicles are the starting point of follicular development and the basic functional
unit of female reproduction. Primordial follicles are formed around birth, and most of the …

Cigarette smoking killed about 8 million people every year and promoted non-small cell lung
cancer (NSCLC). We investigated the molecular mechanism of smoking-promoted NSCLC …

Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …

Abstract Background The 3-deoxysappanchalcone (3-DSC), a chemical separated from
Caesalpinia sappan L, has been substantiated to display anti-inflammatory, anti-influenza …

Simple Summary The indolent nature of some cancers makes early detection challenging,
as such significant effort is placed on identifying circulating cancer biomarkers using …

Carotenoids, known for their antioxidant properties, have garnered significant attention for
their potential antitumour activities. This comprehensive review aims to elucidate the diverse …