New approaches to chronic hepatitis B

G Dusheiko, K Agarwal, MK Maini - New England Journal of …, 2023 - Mass Medical Soc
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Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?

J Hou, M Karin, B Sun - Nature reviews Clinical oncology, 2021 - nature.com
The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …

Hepatitis B virus-associated hepatocellular carcinoma

GEM Rizzo, G Cabibbo, A Craxì - Viruses, 2022 - mdpi.com
Hepatitis B virus (HBV) is DNA-based virus, member of the Hepadnaviridae family, which
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …

Hepatocellular carcinoma in chronic viral hepatitis: where do we stand?

FP Russo, A Zanetto, E Pinto, S Battistella… - International journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

Clinical significance of adverse events for patients with unresectable hepatocellular carcinoma treated with lenvatinib: a multicenter retrospective study

S Shimose, H Iwamoto, T Niizeki, T Shirono, Y Noda… - Cancers, 2020 - mdpi.com
We sought to investigate the clinical profile (s) associated with the discontinuation of
lenvatinib (LEN) due to severe adverse events (DLSAE) in patients with unresectable …

Coexpression of CMTM6 and PD-L1 as a predictor of poor prognosis in macrotrabecular-massive hepatocellular carcinoma

LL Liu, SW Zhang, X Chao, CH Wang, X Yang… - Cancer Immunology …, 2021 - Springer
Abstract The “macrotrabecular-massive”(MTM) pattern of hepatocellular carcinoma (HCC)
has been suggested to represent a distinct HCC subtype and is associated with specific …

[HTML][HTML] Golgi protein-73: A biomarker for assessing cirrhosis and prognosis of liver disease patients

NK Gatselis, T Tornai, Z Shums, K Zachou… - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Reliable biomarkers of cirrhosis, hepatocellular carcinoma (HCC), or
progression of chronic liver diseases are missing. In this context, Golgi protein-73 (GP73) …

[HTML][HTML] The safety and efficacy of lenvatinib combined with immune checkpoint inhibitors therapy for advanced hepatocellular carcinoma

Y Wang, M Jiang, J Zhu, J Qu, K Qin, D Zhao… - Biomedicine & …, 2020 - Elsevier
China has one of the highest incidence rates of hepatocellular carcinoma (HCC) in the
world. As most patients are diagnosed with advanced or unretractable HCC, systematic …