[HTML][HTML] Metastatic and triple-negative breast cancer: challenges and treatment options

S Al-Mahmood, J Sapiezynski, OB Garbuzenko… - Drug delivery and …, 2018 - Springer
The major current conventional types of metastatic breast cancer (MBC) treatments include
surgery, radiation, hormonal therapy, chemotherapy, or immunotherapy. Introducing …

Breast cancer in young women: an overview

Z Anastasiadi, GD Lianos, E Ignatiadou, HV Harissis… - Updates in surgery, 2017 - Springer
Despite dramatic advances in cancer research setting, breast cancer remains a major health
problem and represents currently a top biomedical research priority. Worldwide, breast …

[HTML][HTML] Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway

CH Lin, CY Chang, KR Lee, HJ Lin, TH Chen, L Wan - BMC cancer, 2015 - Springer
Background Flavones found in plants display various biological activities, including anti-
allergic, anti-viral, anti-inflammatory, anti-oxidation, and anti-tumor effects. In this study, we …

[HTML][HTML] Disulfiram modulates ROS accumulation and overcomes synergistically cisplatin resistance in breast cancer cell lines

Z Yang, F Guo, AE Albers, J Sehouli… - Biomedicine & …, 2019 - Elsevier
The chemotherapeutic agent cisplatin typically induces apoptosis by inhibiting the cell cycle.
Cancer Stem Cells (CSCs), which are a proliferative quiescent and slowly-cycling cell …

[HTML][HTML] Medicinal herbs used in traditional management of breast cancer: Mechanisms of action

DA McGrowder, FG Miller, CR Nwokocha… - Medicines, 2020 - mdpi.com
Background: Breast cancer is one of the principal causes of death among women and there
is a pressing need to develop novel and effective anti-cancer agents. Natural plant products …

Psychosocial issues experienced by young women with breast cancer: the minority group with the majority of need

S Ahmad, K Fergus, M McCarthy - Current opinion in supportive …, 2015 - journals.lww.com
Young women with breast cancer are at greater risk for psychosocial adjustment problems,
yet their needs are often overlooked. Proactive discussions by healthcare providers early on …

[HTML][HTML] Anti-müllerian hormone levels and evolution in women of reproductive age with breast cancer treated with chemotherapy

T Fréour, P Barrière, D Masson - European journal of cancer, 2017 - Elsevier
Background Long-term consequences of cancer treatments in young women, and especially
fertility issues, are gaining attention as survival rates increase. Breast cancer is the most …

Linking DNA damage and hormone signaling pathways in cancer

MJ Schiewer, KE Knudsen - Trends in Endocrinology & Metabolism, 2016 - cell.com
DNA damage response and repair (DDR) is a tightly controlled process that serves as a
barrier to tumorigenesis. Consequently, DDR is frequently altered in human malignancy …

PD-L1 expression and tumor-infiltrating lymphocytes in breast cancer: clinicopathological analysis in women younger than 40 years old

ZOI Evangelou, A Papoudou-Bai, G Karpathiou… - in vivo, 2020 - iv.iiarjournals.org
Background/Aim: To evaluate the association between programmed cell death ligand 1 (PD-
L1) expression on both tumor cells (TC) and inflammatory cells (IC), tumor infiltrating …

[HTML][HTML] Age-related differences in breast cancer mortality according to race/ethnicity, insurance, and socioeconomic status

Y San Miguel, SL Gomez, JD Murphy, RB Schwab… - BMC cancer, 2020 - Springer
Background We assessed breast cancer mortality in older versus younger women according
to race/ethnicity, neighborhood socioeconomic status (nSES), and health insurance status …