Endothelial-to-Mesenchymal Transition in Cardiovascular Pathophysiology

A Singh, KS Bhatt, HC Nguyen, JC Frisbee… - International Journal of …, 2024 - mdpi.com
Under different pathophysiological conditions, endothelial cells lose endothelial phenotype
and gain mesenchymal cell-like phenotype via a process known as endothelial-to …

Different Mechanisms in Doxorubicin-Induced Cardiomyopathy: Impact of BRCA1 and BRCA2 Mutations

HC Nguyen, JC Frisbee, KK Singh - Hearts, 2024 - mdpi.com
Germline mutations in Breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2)
cause breast, ovarian, and other cancers, and the chemotherapeutic drug doxorubicin (Dox) …

Protein Disulfide Isomerase 4 Is an Essential Regulator of Endothelial Function and Survival

S Bu, A Singh, HC Nguyen, B Peddi, K Bhatt… - International Journal of …, 2024 - mdpi.com
Endothelial autophagy plays an important role in the regulation of endothelial function. The
inhibition of endothelial autophagy is associated with the reduced expression of protein …

[HTML][HTML] Peripheral whole blood microRNA expression in relation to vascular function: a population-based study

V Talevi, K Melas, G Pehlivan, MA Imtiaz… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background As key regulators of gene expression, microRNAs affect many cardiovascular
mechanisms and have been associated with several cardiovascular diseases. In this study …