Mouse models are the basis of preclinical and translational research in hepatocellular
carcinoma (HCC). Multiple methods exist to induce tumour formation in mice, including …

Alcoholic liver disease (ALD) is a major cause of acute and chronic liver injury. Extensive
evidence has been accumulated on the pathological process of ALD during the past …

Objective Acute kidney injury (AKI) is a common complication of acute liver failure (ALF).
Pyroptosis is a necrosis type related to inflammation. This study aimed to investigate the role …

Several scientific and clinical studies have shown an association between chronic alcohol
consumption and the occurrence of cancer in humans. The mechanism for alcohol-induced …

Hepatocellular carcinoma (HCC) has been identified as one of the most deadly
malignancies with limited therapeutic efficacy worldwide. However, understanding the …

Neutrophils are the largest population of circulating leukocytes and the first responder
against invading pathogens or other danger signals. Sophisticated machineries help them …

Background Alcohol is classified as a Group 1 carcinogen by the International Agency for
Research on Cancer because it induces hepatocellular carcinoma (among other cancers) in …

Alcoholic liver disease (ALD) is the most common chronic liver disease in the Western world,
and it persists at a high prevalence. Understanding the pathophysiology and successful …

Genistein (Gen) is one of the most potent soy isoflavones used for hepatocellular carcinoma
(HCC) treatment. Low aqueous solubility and first-pass metabolism are the main obstacles …

Hepatocellular carcinoma (HCC) is a common malignant tumor with insidious early
symptoms, easy metastasis, postoperative recurrence, poor drug efficacy, and a high drug …