Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats

H Wang, A Wisneski, AM Imbrie-Moore… - Journal of the …, 2022 - Elsevier
After myocardial infarction (MI), adult mammals exhibit scar formation, adverse left
ventricular (LV) remodeling, LV stiffening, and impaired contractility, ultimately resulting in …

The expanding armamentarium of innovative bioengineered strategies to augment cardiovascular repair and regeneration

S Elde, H Wang, YJ Woo - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Cardiovascular disease remains the leading cause of death worldwide. While clinical trials
of cell therapy have demonstrated largely neutral results, recent investigations into the …

[HTML][HTML] Bioengineered analog of stromal cell-derived factor 1α preserves the biaxial mechanical properties of native myocardium after infarction

H Wang, A Wisneski, MJ Paulsen… - Journal of the …, 2019 - Elsevier
Adverse remodeling of the left ventricle (LV) after myocardial infarction (MI) results in
abnormal tissue biomechanics and impaired cardiac function, often leading to heart failure …

A tissue-engineered chondrocyte cell sheet induces extracellular matrix modification to enhance ventricular biomechanics and attenuate myocardial stiffness in …

Y Shudo, JE Cohen, JW MacArthur… - … Engineering Part A, 2015 - liebertpub.com
There exists a substantial body of work describing cardiac support devices to mechanically
support the left ventricle (LV); however, these devices lack biological effects. To remedy this …

Multiaxial lenticular stress-strain relationship of native myocardium is preserved by infarct-induced natural heart regeneration in neonatal mice

H Wang, R Bennett-Kennett, MJ Paulsen… - Scientific Reports, 2020 - nature.com
Neonatal mice exhibit natural heart regeneration after myocardial infarction (MI) on postnatal
day 1 (P1), but this ability is lost by postnatal day 7 (P7). Cardiac biomechanics intricately …

[PDF][PDF] 趋化因子CXCL12/趋化因子受体CXCR7 轴与心血管疾病的相关性

涂小丽, 吴延庆 - 重庆医科大学学报, 2015 - cyxb.alljournals.ac.cn
趋化因子CXCL12 (chemokine CXCL12, CXCL12) 是& 种能诱导细胞向高浓度方向定向运动的
小分子多肤类物质, 研究表明其能够通过调节造血干细胞, 祖细胞的归巢 …

ANGIOGENIC CYTOKINES IN THE TREATMENT OF ISCHEMIC HEART DISEASE

MJ Paulsen, YJ Woo - Engineering Stem Cells For Tissue …, 2017 - books.google.com
Approximately 15.5 million American adults suffer from coronary artery disease, a number
that is expected to increase over 18% by 2030.1 Over the past several decades, the mortality …

[引用][C] CXCL12 基因rs2839688 位点多态性与冠心病的关系

许宗磊, 冯桂青, 蔡文芝, 闫忠华, 侯桂英 - 山东医药, 2016