Biological strategies for oligo/polysaccharide synthesis: Biocatalyst and microbial cell factory

L Zhao, Z Ma, J Yin, G Shi, Z Ding - Carbohydrate Polymers, 2021 - Elsevier
Oligosaccharides and polysaccharides constitute the principal components of
carbohydrates, which are important biomacromolecules that demonstrate considerable …

An efficient modular one-pot synthesis of heparin-based anticoagulant idraparinux

S Dey, HJ Lo, CH Wong - Journal of the American Chemical …, 2019 - ACS Publications
Idraparinux is a fully O-sulfated α-methyl glycoside of heparin pentasaccharide motif known
to interact with the antithrombin III domain and act as anticoagulant. The current most …

TsOH-catalyzed acyl migration reaction of the Bz-group: innovative assembly of various building blocks for the synthesis of saccharides

XY Liang, AL Liu, HJS Fan, L Wang, ZN Xu… - Organic & …, 2023 - pubs.rsc.org
We developed an efficient method to achieve the regioselective acyl migration of benzoyl
ester. In all the cases, the reactions required only the commercially available organic acid …

Production of enantiopure chiral aryl heteroaryl carbinols using whole‐cell Lactobacillus paracasei biotransformation

E Şahin - Synthetic Communications, 2020 - Taylor & Francis
Aryl and heteroaryl chiral carbinols are useful precursors in the synthesis of drugs.
Lactobacillus paracasei BD87E6, which is obtained from a cereal based fermented …

Asymmetric reduction of prochiral aromatic and hetero aromatic ketones using whole-cell of Lactobacillus senmaizukei biocatalyst

NS Çolak, E Kalay, E Şahin - Synthetic Communications, 2021 - Taylor & Francis
Asymmetric bioreduction of aromatic and heteroaromatic ketones is an important process in
the production of precursors of biologically active molecules. In this study, the bioreduction …

Reactions of Aldehydes and Ketones and their Derivatives

BA Murray - Organic Reaction Mechanisms 2011: An annual …, 2014 - Wiley Online Library
Carbohydrate‐based benzylidene acetals undergo reductive ring opening. 1‐β‐O‐Acyl
glucoside conjugates of phenylacetic acids have been synthesized, and their acyl migration …

Synthesis of glycoimmunogen Tn-Thr-PS A1 via hydrazone bond and stability optimization of PS A1 monosaccharide mimics under vaccine development conditions

F Hossain, S Nishat, S Ghosh, S Boga… - Journal of …, 2020 - Taylor & Francis
Previously, our group constructed several immunogens utilizing oxime linkage to conjugate
a T-cell stimulatory zwitterionic polysaccharide PS A1 and tumor associated carbohydrate …

Chemoenzymatische Synthese unsymmetrischer N-Glycanazide

C Spies - 2023 - epub.uni-bayreuth.de
Glycosylierungen gehören zu den wichtigsten posttranslationalen Modifikationen von
Proteinen und tragen maßgeblich zu deren Eigenschaften und Stabilität bei. Für die Analyse …

Rhizopus arrhizus mediated SAR studies in chemoselective biotransformation of haloketones at ambient temperature

PR Salokhe, RS Salunkhe - Biocatalysis and Biotransformation, 2022 - Taylor & Francis
We have demonstrated a green chemistry approach using the fungus Rhizopus arrhizus for
the reductive dehalogenation and synthesis of chiral secondary carbinols and halohydrins of …