Opportunities, barriers, and recommendations in Down syndrome research

JA Hendrix, A Amon, L Abbeduto… - … science of rare …, 2020 - content.iospress.com
BACKGROUND: Recent advances in medical care have increased life expectancy and
improved the quality of life for people with Down syndrome (DS). These advances are the …

Health outcomes of physical activity interventions in adults with down syndrome: A systematic review

BK Ballenger, EE Schultz, M Dale… - Adapted Physical …, 2023 - journals.humankinetics.com
This systematic review examined whether physical activity interventions improve health
outcomes in adults with Down syndrome (DS). We searched PubMed, APA PsycInfo …

Multiple morbidity across the lifespan in people with Down syndrome or intellectual disabilities: a population-based cohort study using electronic health records

RA Baksh, SE Pape, LF Chan, AA Aslam… - The Lancet Public …, 2023 - thelancet.com
Summary Background The Down syndrome phenotype is well established, but our
understanding of its morbidity patterns is limited. We comprehensively estimated the risk of …

Physical activity patterns in adults with Down Syndrome

NM Oreskovic, C Cottrell, A Torres… - Journal of Applied …, 2020 - Wiley Online Library
Abstract Background Individuals with Down syndrome (DS) are less physically active than
the general population, but limited data on objective physical activity patterns in adults with …

[HTML][HTML] Physiotherapy management of Down syndrome

N Shields - Journal of physiotherapy, 2021 - Elsevier
Over the past century, the life expectancy of people born with Down syndrome has
increased from 9 to 60 years, 1 with data indicating that it could match the general …

Resistance training and Down Syndrome: A narrative review on considerations for exercise prescription and safety

GLR Melo, IVS Neto, EF Fonseca, W Stone… - Frontiers in …, 2022 - frontiersin.org
The current manuscript reviews the literature on the health effects of resistance training (RT)
for individuals with Down syndrome (DS), focusing on this training modality's methodology …

Anthropometry does not fully explain low fitness among adults with Down syndrome

VDY Beck, T Baynard, EC Lefferts… - Journal of …, 2021 - Wiley Online Library
Background Cardiorespiratory fitness, expressed as peak oxygen uptake during exercise
(VO2peak), is an important predictor of cardiovascular health and is related to …

Hemodynamic and cardiorespiratory responses to submaximal and maximal exercise in adults with Down syndrome

GR Oviedo, M Carbó-Carreté, M Guerra-Balic… - Frontiers in …, 2022 - frontiersin.org
Introduction: The genetic disorder causing Down syndrome (DS) affects the
cardiorespiratory and hemodynamic parameters. When exercising, sufficient blood flow is …

Cardiorespiratory coordination during exercise in adults with Down syndrome

GR Oviedo, S Garcia-Retortillo… - Frontiers in …, 2021 - frontiersin.org
Introduction: Down syndrome (DS) is a chromosomal disorder affecting simultaneously
cardiovascular and respiratory systems. There is no research studying the coupling between …

Comprehensive cardiopulmonary profile of individuals with Down syndrome

VDY Beck, SO Wee, EC Lefferts… - Journal of …, 2022 - Wiley Online Library
Abstract Background Individuals with Down syndrome (DS) have low levels of
cardiorespiratory fitness and previous studies have shown that these low levels of fitness …