Despite advances in pharmacologic and device treatment of chronic heart failure, long-term
morbidity and mortality remain high, and many patients progress to end-stage heart failure …

Abstract Purpose of Review The purpose of this review is to provide a comprehensive
update on recent advances in heart transplantation. Recent Findings Heart transplantation is …

Despite advances in medical and device therapy, the prognosis and quality of life of patients
with advanced heart failure (HF) remains poor. For a carefully selected group of these …

Since the first heart transplantation (HT) in 1967, survival has steadily improved. Issues
related to over-and under-immunosuppression are, however, still common following HT …

Significant practice-changing developments have occurred in the care of heart
transplantation candidates and recipients over the past decade. This Canadian …

High inter-individual variability in tacrolimus clearance is attributed to genetic
polymorphisms of CYP3A enzymes. However, due to CYP3A phenoconversion induced by …

Recent advances in the management of heart transplant recipients have resulted in
improved survival, particularly in the early post-transplant period. Although graft rejection …

Background: With an aging population, the prevalence of heart failure continues to rise. The
use of guideline-directed medical therapy and mechanical circulatory support devices has …

Heart transplantation is the standard of therapy for patients with end-stage heart disease.
Since the first human-to-human heart transplantation, performed in 1967, advances in organ …

Bone mineral density (BMD) in the lumbar spine and femoral neck, the incidence of
osteoporosis, and survival up to 10 years after heart transplantation (HT) were investigated …