Options of the main derivatization approaches for analytical ESI and MALDI mass spectrometry

VG Zaikin, RS Borisov - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

Progress and challenges in quantifying carbonyl-metabolomic phenomes with LC-MS/MS

Y Sun, H Tang, Y Wang - Molecules, 2021 - mdpi.com
Carbonyl-containing metabolites widely exist in biological samples and have important
physiological functions. Thus, accurate and sensitive quantitative analysis of carbonyl …

Improved ion mobility separation and structural characterization of steroids using derivatization methods

DC Velosa, AJ Dunham, ME Rivera… - Journal of the …, 2022 - ACS Publications
Steroids are an important class of biomolecules studied for their role in metabolism,
development, nutrition, and disease. Although highly sensitive GC-and LC-MS/MS-based …

Determination of the steroid profile in alternative matrices by liquid chromatography tandem mass spectrometry

A Gomez-Gomez, J Miranda, G Feixas… - The Journal of Steroid …, 2020 - Elsevier
The simultaneous determination of a broad panel of steroids provides more accurate
information about the hormonal status than the detection of a single hormone. For that …

Stability and detectability of testosterone esters in dried blood spots after intramuscular injections

SA Solheim, MCS Levernæs… - Drug Testing and …, 2022 - Wiley Online Library
While misuse of testosterone esters is widespread in elite and recreational sports, direct
detection of intact testosterone esters in doping control samples is hampered by the rapid …

Analytics for steroid hormone profiling in body fluids

A Temerdashev, E Dmitrieva, I Podolskiy - Microchemical Journal, 2021 - Elsevier
The present article focuses on the most commonly used and perspective methods (including
non-chromatographic assays) for steroids quantification in different matrices. The main …

[HTML][HTML] Quantification of glucocorticoid and progestogen metabolites in bovine plasma, skimmed milk and saliva by UHPLC-HR-MS with polarity switching

K Rehm, AK Hankele, SE Ulbrich, L Bigler - Analytica Chimica Acta, 2024 - Elsevier
Steroid metabolites are increasingly in focus when searching for novel biomarkers in
physiological mechanisms and their disorders. While major steroids such as progesterone …

Parallel derivatization strategy coupled with liquid chromatography-mass spectrometry for broad coverage of steroid hormones

Q Qin, D Feng, C Hu, B Wang, M Chang, X Liu… - … of Chromatography a, 2020 - Elsevier
Steroid hormones are a type of crucial substances that mediate numerous vital physiological
functions. The comprehensive detection of steroid hormones can help understand the …

Mass spectrometry based on chemical derivatization has brought novel discoveries to lipidomics: A comprehensive review

D Wang, H Xiao, X Lv, H Chen, F Wei - Critical Reviews in …, 2023 - Taylor & Francis
Lipids, as one of the most important organic compounds in organisms, are important
components of cells and participate in energy storage and signal transduction of living …

Online Charge-Generation Derivatization by Electrochemical Radical Cations of Thianthrene: Mass Spectrometry Imaging of Estrogens in Biological Tissues

Y Liu, J Bai, X Dong, Y Cao, M Bao, Y Lu… - Analytical …, 2024 - ACS Publications
Estrogens play a significant role in endocrinology and oncology. Although separation
methods coupled with mass spectrometry (MS) have emerged as a powerful tool for studying …