Background and aim Narcolepsy is an uncommon hypothalamic disorder of presumed
autoimmune origin that usually requires lifelong treatment. This paper aims to provide …

Narcolepsy with cataplexy is a disabling sleep disorder affecting 0· 02% of adults worldwide.
It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone …

Background Although continuous positive airway pressure (CPAP) has become the
standard of care in the treatment of obstructive sleep apnea (OSA), 2 systematic reviews …

Quality of life is a major outcome variable in choosing and evaluating treatment alternatives
for sleep disorders. However, the number of well validated and sufficiently responsive …

Objective: To assess the efficacy and safety of modafinil for the treatment of fatigue in
multiple sclerosis (MS). Methods: Patients aged 18–65 years with a diagnosis of MS, a …

Introduction Obstructive sleep apnea (OSA) is a widely prevalent sleep-related breathing
disorder, which leads to several life-threatening diseases. OSA has systemic effects on …

Despite years of active research, there are still no approved medications for the treatment of
cocaine dependence. Modafinil is a glutamate-enhancing agent that blunts cocaine …

Existe una estrecha interrelación entre los procesos de sueño y el estado general de salud
física y psicológica de una persona. En el presente artículo se revisan algunas de las …

Cataplexy is the pathognomonic symptom of narcolepsy, and is the sudden uncontrollable
onset of skeletal muscle paralysis or weakness during wakefulness. Cataplexy is …

Management of narcolepsy with or without cataplexy relies on several classes of drugs,
namely stimulants for excessive daytime sleepiness and irresistible episodes of sleep …