APT‐weighted MRI: techniques, current neuro applications, and challenging issues

J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …

Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

Chemical exchange saturation transfer (CEST): what is in a name and what isn't?

PCM Van Zijl, NN Yadav - Magnetic resonance in medicine, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is a relatively new magnetic
resonance imaging contrast approach in which exogenous or endogenous compounds …

Clinical applications of chemical exchange saturation transfer (CEST) MRI

KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …

Magnetic resonance imaging of glutamate

K Cai, M Haris, A Singh, F Kogan, JH Greenberg… - Nature medicine, 2012 - nature.com
Glutamate, a major neurotransmitter in the brain, shows a pH-and concentration-dependent
chemical exchange saturation transfer effect (GluCEST) between its amine group and bulk …

MR thermometry

V Rieke, K Butts Pauly - … Imaging: An Official Journal of the …, 2008 - Wiley Online Library
Minimally invasive thermal therapy as local treatment of benign and malignant diseases has
received increasing interest in recent years. Safety and efficacy of the treatment require …

Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods

M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …

Inverse Z‐spectrum analysis for spillover‐, MT‐, and T1‐corrected steady‐state pulsed CEST‐MRI – application to pH‐weighted MRI of acute stroke

M Zaiss, J Xu, S Goerke, IS Khan, RJ Singer… - NMR in …, 2014 - Wiley Online Library
Endogenous chemical exchange saturation transfer (CEST) effects are always diluted by
competing effects, such as direct water proton saturation (spillover) and semi‐solid …

Alternatives to gadolinium-based metal chelates for magnetic resonance imaging

S Viswanathan, Z Kovacs, KN Green… - Chemical …, 2010 - ACS Publications
Magnetic resonance imaging (MRI) has been immensely valuable in diagnostic clinical
imaging over the last few decades owing to its exceptional spatial and anatomical …

Nuts and bolts of chemical exchange saturation transfer MRI

G Liu, X Song, KWY Chan… - NMR in Biomedicine, 2013 - Wiley Online Library
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast
mechanism that is well suited for molecular imaging studies. This new mechanism can be …