Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control

L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

[HTML][HTML] GDNF–Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

ER Kramer, B Liss - Febs Letters, 2015 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) and its canonical receptor Ret can signal
together or independently to fulfill many important functions in the midbrain dopaminergic …

A review of the role of cav-1 in neuropathology and neural recovery after ischemic stroke

Q Huang, W Zhong, Z Hu, X Tang - Journal of neuroinflammation, 2018 - Springer
Ischemic stroke starts a series of pathophysiological processes that cause brain injury.
Caveolin-1 (cav-1) is an integrated protein and locates at the caveolar membrane. It has …

Functional role of KLF10 in multiple disease processes

M Subramaniam, JR Hawse, NM Rajamannan… - Biofactors, 2010 - Wiley Online Library
Since the discovery by this laboratory of the zinc finger transcription factor, KLF10, a member
of the Krüppel-like family of transcription factors, there have been multiple publications …

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

S Carnicella, V Kharazia, J Jeanblanc… - Proceedings of the …, 2008 - National Acad Sciences
Previously, we demonstrated that the action of the natural alkaloid, ibogaine, to reduce
alcohol (ethanol) consumption is mediated by the glial cell line-derived neurotrophic factor …

Biomaterials used in stem cell therapy for spinal cord injury

A Higuchi, SS Kumar, G Benelli, QD Ling, HF Li… - Progress in Materials …, 2019 - Elsevier
Spinal cord injury (SCI) is a common, severe damage to the central nervous system. Here,
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …

Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds

TY Wang, JS Forsythe, DR Nisbet, CL Parish - Biomaterials, 2012 - Elsevier
With the brain's limited capacity for repair, new and innovative approaches are required to
promote regeneration. While neural transplantation for a number of neural disease/injuries …

Subcellular rearrangement of hsp90‐binding immunophilins accompanies neuronal differentiation and neurite outgrowth

HR Quintá, D Maschi, C Gomez‐Sanchez… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 716–734. Abstract FKBP51 and FKBP52 (FK506‐binding protein
51 and 52) are tetratricopeptide repeat‐domain immunophilins belonging to the …

[HTML][HTML] Long-term exposure to GDNF induces dephosphorylation of Ret, AKT, and ERK1/2, and is ineffective at protecting midbrain dopaminergic neurons in cellular …

V Mesa-Infante, D Afonso-Oramas… - Molecular and Cellular …, 2022 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) promotes differentiation, proliferation, and
survival in different cell types, including dopaminergic neurons. Thus, GDNF has been …

The non-survival effects of glial cell line-derived neurotrophic factor on neural cells

D Cortés, OA Carballo-Molina… - Frontiers in Molecular …, 2017 - frontiersin.org
Glial cell line-derived neurotrophic factor (GDNF) was first characterized as a survival-
promoting molecule for dopaminergic neurons (DANs). Afterwards, other cells were also …