Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control
L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …
including motor control, modulation of affective and emotional states, reward mechanisms …
[HTML][HTML] GDNF–Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease
ER Kramer, B Liss - Febs Letters, 2015 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) and its canonical receptor Ret can signal
together or independently to fulfill many important functions in the midbrain dopaminergic …
together or independently to fulfill many important functions in the midbrain dopaminergic …
A review of the role of cav-1 in neuropathology and neural recovery after ischemic stroke
Q Huang, W Zhong, Z Hu, X Tang - Journal of neuroinflammation, 2018 - Springer
Ischemic stroke starts a series of pathophysiological processes that cause brain injury.
Caveolin-1 (cav-1) is an integrated protein and locates at the caveolar membrane. It has …
Caveolin-1 (cav-1) is an integrated protein and locates at the caveolar membrane. It has …
Functional role of KLF10 in multiple disease processes
M Subramaniam, JR Hawse, NM Rajamannan… - Biofactors, 2010 - Wiley Online Library
Since the discovery by this laboratory of the zinc finger transcription factor, KLF10, a member
of the Krüppel-like family of transcription factors, there have been multiple publications …
of the Krüppel-like family of transcription factors, there have been multiple publications …
GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse
Previously, we demonstrated that the action of the natural alkaloid, ibogaine, to reduce
alcohol (ethanol) consumption is mediated by the glial cell line-derived neurotrophic factor …
alcohol (ethanol) consumption is mediated by the glial cell line-derived neurotrophic factor …
Biomaterials used in stem cell therapy for spinal cord injury
A Higuchi, SS Kumar, G Benelli, QD Ling, HF Li… - Progress in Materials …, 2019 - Elsevier
Spinal cord injury (SCI) is a common, severe damage to the central nervous system. Here,
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …
Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds
With the brain's limited capacity for repair, new and innovative approaches are required to
promote regeneration. While neural transplantation for a number of neural disease/injuries …
promote regeneration. While neural transplantation for a number of neural disease/injuries …
Subcellular rearrangement of hsp90‐binding immunophilins accompanies neuronal differentiation and neurite outgrowth
HR Quintá, D Maschi, C Gomez‐Sanchez… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 716–734. Abstract FKBP51 and FKBP52 (FK506‐binding protein
51 and 52) are tetratricopeptide repeat‐domain immunophilins belonging to the …
51 and 52) are tetratricopeptide repeat‐domain immunophilins belonging to the …
[HTML][HTML] Long-term exposure to GDNF induces dephosphorylation of Ret, AKT, and ERK1/2, and is ineffective at protecting midbrain dopaminergic neurons in cellular …
V Mesa-Infante, D Afonso-Oramas… - Molecular and Cellular …, 2022 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) promotes differentiation, proliferation, and
survival in different cell types, including dopaminergic neurons. Thus, GDNF has been …
survival in different cell types, including dopaminergic neurons. Thus, GDNF has been …
The non-survival effects of glial cell line-derived neurotrophic factor on neural cells
D Cortés, OA Carballo-Molina… - Frontiers in Molecular …, 2017 - frontiersin.org
Glial cell line-derived neurotrophic factor (GDNF) was first characterized as a survival-
promoting molecule for dopaminergic neurons (DANs). Afterwards, other cells were also …
promoting molecule for dopaminergic neurons (DANs). Afterwards, other cells were also …