In recent decades, transient and highly reactive ortho-quinodimethanes (o-QDMs), ortho-
quinone methides (o-QMs) and aza-ortho-quinone methides (aza-o-QMs) have attracted …

Heterocycles are a ubiquitous substructure in organic small molecules designed for use in
materials and medicines. Recent work in catalysis has focused on enabling access to new …

Chiral tetrahydrocarbazoles (THCs) are prevalent in numerous natural indole alkaloids as
well as synthetic pharmaceuticals, and exhibit a broad spectrum of bioactivities. As such, the …

An efficient aminocatalytic enantioselective double-activation strategy has been developed
that combines several different aminocatalytic modes in a cascade process, such as iminium …

In the presence of copper sulfate, the three-component reaction of aromatic aldehydes,
ethylindole-3-acetate and 4-arylidene-5-methyl-2-phenylpyrazol-3-ones, in refluxing toluene …

The C (sp2)–H function of indole ketone with diazo compound via a rhodium (II)-catalyzed
intramolecular electrophilic trapping reaction under mild conditions in air was demonstrated …

Tetrahydrocarbazole and its derivatives have received much attention due to the prevalence
of this scaffold in natural products and their use in organic synthesis. We have developed a …

A practical and effective copper-catalyzed dehydrogenative Diels–Alder reaction of gem-
diesters and ketone with dienes has been established. The active dienophiles were …

Functionalized spiro [carbazole-3, 5′-pyrimidines] and spiro [carbazole-3, 1′-
cyclohexanes] were efficiently synthesized in satisfactory yields with high …

A carbene-catalyzed enantioselective cascade reaction of substituted
methylenemalononitriles and α-bromoenals is disclosed. Key steps of this cascade process …