The SAMP1/YitFc mouse strain represents a model of Crohn's disease (CD)-like ileitis that is
ideal for investigating the pathogenesis of chronic intestinal inflammation. Different from the …

Crohn's disease and ulcerative colitis, together known as inflammatory bowel disease, are
debilitating chronic disorders of unknown cause and cure. Our evolving understanding of …

Background & Aims Interleukin (IL) 33/IL1F11 is an important mediator for the development
of type 2 T-helper cell (Th2)–driven inflammatory disorders and has also been implicated in …

The RIPK2 kinase transduces signaling downstream of the intracellular peptidoglycan
sensors NOD1 and NOD2 to promote a productive inflammatory response. However …

Intestinal fibrosis is a common complication of the inflammatory bowel diseases (IBDs),
contributing to tissue stiffening and luminal narrowing. Human nuclear receptor 4A 1 …

Crohn's disease and ulcerative colitis are chronic and progressive inflammatory bowel
diseases (IBDs) that are attributed to dysregulated interactions between the gut microbiome …

Inflammatory bowel diseases (IBD) are chronic, relapsing conditions of multifactorial
etiology. The two primary diseases of IBD are Crohn's disease (CD) and ulcerative colitis …

Inflammation of the ileum, or ileitis, is commonly caused by Crohn's disease (CD) but can
also accompany ulcerative colitis (backwash ileitis), infections or drug-related damage …

Simple Summary Gastric cancer is one of the most prevalent and deadliest neoplasms
worldwide. Although significant advances have been made in recent decades to improve its …

Senescence-accelerated mice P1 (SAMP1) is an aging model characterized by shortened
lifespan and early signs of senescence. Klotho is an aging-suppressor gene. The purpose of …