Molecular genetics of abnormal redox homeostasis in type 2 diabetes mellitus
I Azarova, A Polonikov, E Klyosova - International Journal of Molecular …, 2023 - mdpi.com
Numerous studies have shown that oxidative stress resulting from an imbalance between
the production of free radicals and their neutralization by antioxidant enzymes is one of the …
the production of free radicals and their neutralization by antioxidant enzymes is one of the …
Artificial intelligence perspective in the future of endocrine diseases
M Hasanzad, HR Aghaei Meybodi, N Sarhangi… - Journal of Diabetes & …, 2022 - Springer
In recent years, artificial intelligence (AI) shows promising results in the diagnosis,
prediction, and management of diseases. The move from handwritten medical notes to …
prediction, and management of diseases. The move from handwritten medical notes to …
KCNJ11 and KCNQ1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes Mellitus
S Majcher, P Ustianowski, D Malinowski, M Czerewaty… - Genes, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) represents carbohydrate intolerance in pregnant
women. The pathogenesis of GDM is very complex, but abnormalities in insulin production …
women. The pathogenesis of GDM is very complex, but abnormalities in insulin production …
Association of KCNQ1rs2237892C⟶ T Gene with Type 2 Diabetes Mellitus: A Meta‐Analysis
WJ Han, JY Deng, H Jin, LP Yin… - Journal of Diabetes …, 2021 - Wiley Online Library
Background. Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases
in adults, causing high morbidity and mortality worldwide. In recent years, the prevalence of …
in adults, causing high morbidity and mortality worldwide. In recent years, the prevalence of …
Identification of distinct trajectories in preclinical type 2 diabetes and their associations with outcomes
Z Huang - medRxiv, 2024 - medrxiv.org
Type 2 Diabetes Mellitus (T2DM) is increasingly prevalent and significantly impacts patients'
lives. However, the phenotypic and genetic heterogeneity of the preclinical stage of T2DM …
lives. However, the phenotypic and genetic heterogeneity of the preclinical stage of T2DM …
Association between KCNJ11 rs5219 polymorphisms and gestational diabetes mellitus: A meta-analysis
JK Muruganantham, I BK, R Veerabathiran - International Journal of …, 2024 - Springer
Background Gestational diabetes mellitus (GDM), characterized by hyperglycemia during
pregnancy, is influenced by various factors, including genetic predisposition. The potassium …
pregnancy, is influenced by various factors, including genetic predisposition. The potassium …
An overview of the pharmacogenetics of sulfonylurea in type 2 diabetes mellitus
B Aljabali, D Joujeh - Journal of Advanced Pharmacy …, 2024 - aprh.journals.ekb.eg
Background and Objective: Diabetes mellitus (DM) is a prevalent disease, with its
prevalence increasing over the past few decades, posing a significant public health …
prevalence increasing over the past few decades, posing a significant public health …
XPRS: A Tool for Interpretable and Explainable Polygenic Risk Score
NY Kim, S Lee - medRxiv, 2024 - medrxiv.org
The polygenic risk score (PRS) is an important method for assessing genetic susceptibility to
diseases; however, its clinical utility is limited by a lack of interpretability tools. To address …
diseases; however, its clinical utility is limited by a lack of interpretability tools. To address …
Precision medicine path at personalized medicine research center/endocrinology and metabolism research institute: A systematic review
N Sarhangi, S Nikfar, M Hasanzad… - Journal of Diabetes & …, 2021 - Springer
Background Precision medicine is an evolving predictive, early preventive, and treatment
method that takes into account human gene heterogeneity for each individual. Personalized …
method that takes into account human gene heterogeneity for each individual. Personalized …
[PDF][PDF] Influence of KCNQ1 and TCF7L2 genes associated with the role of type 2 diabetes
N Alqadri, NA Abdelmutalab, S Abdelhafeez… - 2022 - academia.edu
T2DM is a long-term metabolic disorder characterized by either the pancreas' inability to
produce enough insulin or the body's inability to properly utilize the insulin it produces. The …
produce enough insulin or the body's inability to properly utilize the insulin it produces. The …