The importance of mitochondrial dynamics, the physiological process of mitochondrial fusion
and fission, in regulating diverse cellular functions and cellular fitness has been well …

Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the
progressive degeneration and death of neurons, leading to a range of neurological …

Mitochondrial oxidative stress plays an important role in the pathogenesis of Alzheimer's
disease (AD). Recently, antioxidant therapy has been considered an effective strategy for …

Echinacoside, a natural phenylethanoid glycoside, was discovered and isolated from the
garden plant Echinacea angustifolia DC., belonging to the Compositae family …

The endoplasmic reticulum (ER) and mitochondria form a unique subcellular compartment
called mitochondria-associated ER membranes (MAMs). Disruption of MAMs impairs Ca2+ …

Glycation is a nonenzymatically catalyzed spontaneous reaction that eventually leads to the
formation of advanced glycation end-products (AGEs), which can bind to the receptor for …

Background Stroke is a globally dangerous disease capable of causing irreversible
neuronal damage with limited therapeutic options. Meldonium, an inhibitor of carnitine …

The disturbance in mitochondrial functions and homeostasis are the major features of
neuron degenerative conditions, like Parkinson's disease, Amyotrophic Lateral Sclerosis …

Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

Ischemic stroke is a serious cerebrovascular disease with high morbidity and mortality. As a
result of ischemia-reperfusion, a cascade of pathophysiological responses is triggered by …