Dysregulation of cellular membrane homeostasis as a crucial modulator of cancer risk
A Erazo‐Oliveras, M Muñoz‐Vega… - The FEBS …, 2024 - Wiley Online Library
Cellular membranes serve as an epicentre combining extracellular and cytosolic
components with membranous effectors, which together support numerous fundamental …
components with membranous effectors, which together support numerous fundamental …
[HTML][HTML] Diversity of Intercellular Communication Modes: A Cancer Biology Perspective
T Ebrahim, AS Ebrahim, M Kandouz - Cells, 2024 - mdpi.com
From the moment a cell is on the path to malignant transformation, its interaction with other
cells from the microenvironment becomes altered. The flow of molecular information is at the …
cells from the microenvironment becomes altered. The flow of molecular information is at the …
NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes
J Fan, J Shi, Y Zhang, J Liu, C An, H Zhu, P Wu… - The EMBO …, 2022 - embopress.org
Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …
Membranes on the move: The functional role of the extracellular vesicle membrane for contact‐dependent cellular signalling
Abstract Extracellular vesicles (EVs), lipid‐enclosed structures released by virtually all life
forms, have gained significant attention due to their role in intercellular and interorganismal …
forms, have gained significant attention due to their role in intercellular and interorganismal …
Understanding immune signaling using advanced imaging techniques
Advanced imaging is key for visualizing the spatiotemporal regulation of immune signaling
which is a complex process involving multiple players tightly regulated in space and time …
which is a complex process involving multiple players tightly regulated in space and time …
[HTML][HTML] Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane
H Yanagisawa, Y Kita, T Oda, M Kikkawa - Communications Biology, 2023 - nature.com
The urothelium, a distinct epithelial tissue lining the urinary tract, serves as an essential
component in preserving urinary tract integrity and thwarting infections. The asymmetric unit …
component in preserving urinary tract integrity and thwarting infections. The asymmetric unit …
[HTML][HTML] Endothelial cell plasma membrane biomechanics mediates effects of pro-inflammatory factors on endothelial mechanosensors: vicious circle formation in …
N Barvitenko, M Ashrafuzzaman, A Lawen… - Membranes, 2022 - mdpi.com
Chronic low-grade vascular inflammation and endothelial dysfunction significantly contribute
to the pathogenesis of cardiovascular diseases. In endothelial cells (ECs), anti-inflammatory …
to the pathogenesis of cardiovascular diseases. In endothelial cells (ECs), anti-inflammatory …
Biophysical Interaction Landscape of Mycobacterial Mycolic Acids and Phenolic Glycolipids with Host Macrophage Membranes
AT Srivatsav, S Kapoor - ACS Applied Bio Materials, 2023 - ACS Publications
Lipidic adjuvant formulations consisting of immunomodulatory mycobacterial cell wall lipids
interact with host cells following administration. The impact of this cross-talk on the host …
interact with host cells following administration. The impact of this cross-talk on the host …
[HTML][HTML] Unveiling Liquid-Crystalline Lipids in the Urothelial Membrane through Cryo-EM
The urothelium, a distinct epithelial tissue lining the urinary tract, serves as an essential
component in preserving urinary tract integrity and thwarting infections. The asymmetric unit …
component in preserving urinary tract integrity and thwarting infections. The asymmetric unit …
[HTML][HTML] Insights into membrane interactions and their therapeutic potential
Recent research into membrane interactions has uncovered a diverse range of therapeutic
opportunities through the bioengineering of human and non-human macromolecules …
opportunities through the bioengineering of human and non-human macromolecules …