Aims Previous studies have demonstrated improved cardiac function following myocardial
infarction (MI) after administration of endothelial progenitor cells (EPCs) into ischaemic …

Inflammatory response in the intima of the artery leads to the release of cytokines, 37 of
which stromal cell–derived factor-1 (also known as chemokine [CXC motif] ligand 12 …

Objectives The clinical translation of cell-based therapies for ischemic heart disease has
been limited because of low cell retention (< 1%) within, and poor targeting to, ischemic …

Perivascular adult stem cells have been isolated from several tissues, including the adult
human brain. They have unique signatures resembling both pericytes and mesenchymal …

Multipotent mesenchymal stem cells have recently emerged as an attractive cell type for the
treatment of diabetes-associated wounds. The purpose of this study was to examine the …

Adult stem cell therapy has demonstrated improved outcomes for treating cardiovascular
diseases in preclinical trials. The development of imaging tools may increase our …

Background—Human induced pluripotent stem cells (iPSCs) are attractive candidates for
therapeutic use, with the potential to replace deficient cells and to improve functional …

Mesenchymal stem cells (MSC) hold promise in promoting vascular regeneration of
ischemic tissue in conditions like critical limb ischemia of the leg. However, this approach …

Stem-cell-based therapies hold considerable promise for regenerative medicine. However,
acute donor-cell death within several weeks after cell delivery remains a critical hurdle for …

Cardioprotection can be evoked through extracardiac approaches. This prompted us to
investigate whether remote transplantation of stem cells confers protection of the heart …