Adaptive laboratory evolution principles and applications in industrial biotechnology

M Mavrommati, A Daskalaki, S Papanikolaou… - Biotechnology …, 2022 - Elsevier
Adaptive laboratory evolution (ALE) is an innovative approach for the generation of evolved
microbial strains with desired characteristics, by implementing the rules of natural selection …

Improving industrial yeast strains: exploiting natural and artificial diversity

J Steensels, T Snoek, E Meersman… - FEMS microbiology …, 2014 - academic.oup.com
Yeasts have been used for thousands of years to make fermented foods and beverages,
such as beer, wine, sake, and bread. However, the choice for a particular yeast strain or …

Mechanisms of ethanol tolerance in Saccharomyces cerevisiae

M Ma, ZL Liu - Applied microbiology and biotechnology, 2010 - Springer
Saccharomyces cerevisiae is a superb ethanol producer, yet is also sensitive to higher
ethanol concentrations especially under high gravity or very high gravity fermentation …

Response and tolerance of yeast to changing environmental stress during ethanol fermentation

P Saini, A Beniwal, A Kokkiligadda, S Vij - Process Biochemistry, 2018 - Elsevier
In development of yeast cell factories, the adequate stress tolerance of the yeast strains is
the universal requirement for industrial fermentation. Primary stress factor is the end product …

Metabolic responses to ethanol in Saccharomyces cerevisiae using a gas chromatography tandem mass spectrometry-based metabolomics approach

H Li, ML Ma, S Luo, RM Zhang, P Han, W Hu - The international journal of …, 2012 - Elsevier
During the fermentation process, Saccharomyces cerevisiae cells are often inhibited by the
accumulated ethanol, and the mechanism of the S. cerevisiae response to ethanol is not …

Reorganization of a synthetic microbial consortium for one-step vitamin C fermentation

EX Wang, MZ Ding, Q Ma, XT Dong, YJ Yuan - Microbial cell factories, 2016 - Springer
Background In the industry, the conventional two-step fermentation method was used to
produce 2-keto-l-gulonic acid (2-KGA), the precursor of vitamin C, by three strains, namely …

Characterization and Role of Sterols in Saccharomyces cerevisiae during White Wine Alcoholic Fermentation

G Girardi Piva, E Casalta, JL Legras, C Tesnière… - Fermentation, 2022 - mdpi.com
Responsible for plasma membrane structure maintenance in eukaryotic organisms, sterols
are essential for yeast development. The role of two sterol sources in Saccharomyces …

Resveratrol Production from Hydrothermally Pretreated Eucalyptus Wood Using Recombinant Industrial Saccharomyces cerevisiae Strains

CE Costa, I Møller-Hansen, A Romaní… - ACS Synthetic …, 2021 - ACS Publications
Resveratrol is a phenolic compound with strong antioxidant activity, being promising for
several applications in health, food, and cosmetics. It is generally extracted from plants or …

Yeast cells in double layer calcium alginate–chitosan microcapsules for sparkling wine production

I Benucci, M Cerreti, D Maresca, G Mauriello, M Esti - Food chemistry, 2019 - Elsevier
This paper focuses on the use of a new type of yeast encapsulation procedure, applying the
chitosan-calcium alginate double layer microcapsules, for the production of Riesling …

Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae

D Stanley, S Fraser, PJ Chambers… - Journal of Industrial …, 2010 - academic.oup.com
Saccharomyces spp. are widely used for ethanologenic fermentations, however yeast
metabolic rate and viability decrease as ethanol accumulates during fermentation …