Individual variation is increasingly recognized as important to psychopathology research.
Concurrently, new methods of analysis based on network models are bringing new …

Abstract Introduction: Patient-reported outcomes (PROs) are of increasing importance in
clinical medicine. However, their evaluation by classic psychometric methods carries …

Background Patients with various psychiatric disorders may suffer from feelings of anger,
sometimes leading to maladaptive (eg, aggressive) behaviors. We examined to what extent …

Objective: The authors evaluated improvement in irritability with antidepressant treatment
and its prognostic utility in treatment-seeking adult outpatients with major depressive …

The intertwined relationship between religion and mental health has been accounted for
since the earliest recorded history. This study aimed to explore the relationship between the …

Introduction Little is known about the epidemiology of aggressive outbursts, including
physical assault, property destruction, and verbal aggression, among adults with unipolar …

Background Research among adults has rarely differentiated between tonic irritability (ie,
irritable mood) and phasic irritability (ie, aggressive outbursts) with respect to multiple …

Background A biological marker of vulnerability should precede onset of illness and be
independent of disease course. We previously reported that cortical thinning may serve as a …

Background Major depressive disorder is an emotional disorder. It is important to improve
our understanding of the role of affect in relapse/recurrence of depression. Therefore, this …

Background The level of depression among drug addicts is generally higher than normal.
Hostility and sense of life meaning may influence depression and become risk factors for …