Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

L Ronnov-Jessen, OW Petersen… - Physiological …, 1996 - journals.physiology.org
Reciprocal interactions between epithelium and mesenchyme mediate crucial aspects of
embryonic development and direct the coordinated organogenesis, correct spatial …

Metallothioneins in human tumors and potential roles in carcinogenesis

MG Cherian, A Jayasurya, BH Bay - Mutation Research/Fundamental and …, 2003 - Elsevier
Metallothioneins (MT) are a group of low-molecular weight, cysteine rich intracellular
proteins, which are encoded by a family of genes containing at least 10 functional isoforms …

Induction, regulation, degradation, and biological significance of mammalian metallothioneins

AT Miles, GM Hawksworth, JH Beattie… - Critical reviews in …, 2000 - Taylor & Francis
MTs are small cysteine-rich metal-binding proteins found in many species and, although
there are differences between them, it is of note that they have a great deal of sequence and …

Dermatofibrosarcoma protuberans

HM Gloster Jr - Journal of the American Academy of Dermatology, 1996 - Elsevier
Dermatofibrosarcoma protuberans is a tumor of intermediate malignancy characterized by
its aggressive local growth and marked propensity to recur after surgical excision. This …

[HTML][HTML] Metallothionein: an overview

N Thirumoorthy, KTM Kumar, AS Sundar… - World journal of …, 2007 - ncbi.nlm.nih.gov
Metallothioneins (MTs) were discovered in 1957 by Margoshes and Vallee and identified as
low-molecular weight and sulphydryl rich proteins. It is not surprising that most mammalian …

[HTML][HTML] Myoepithelial cells: good fences make good neighbors

MC Adriance, JL Inman, OW Petersen… - Breast Cancer Research, 2005 - Springer
The mammary gland consists of an extensively branched ductal network contained within a
distinctive basement membrane and encompassed by a stromal compartment. During …

Metallothionein 2A expression is associated with cell proliferation in breast cancer

R Jin, VTK Chow, PH Tan, ST Dheen, W Duan… - …, 2002 - academic.oup.com
Metallothioneins (MTs) belong to a family of cysteine-rich, metal-binding intracellular
proteins, which have been linked with cell proliferation. In this study, expression levels of the …

Metallothionein expression in human neoplasia

SE Theocharis, AP Margeli, JT Klijanienko… - …, 2004 - Wiley Online Library
The metallothionein family is a class of low‐molecular‐weight, cysteine‐rich proteins with
high affinity for metal ions. Four major isoforms (metallothionein‐1,‐2,‐3, and‐4) have been …

Anticancer drug resistance in primary human brain tumors

M Bredel - Brain Research Reviews, 2001 - Elsevier
The difficult clinical situation still associated with most types of primary human brain tumors
has fostered significant interest in defining novel therapeutic modalities for this …

[HTML][HTML] Metallothionein–immunohistochemical cancer biomarker: a meta-analysis

J Gumulec, M Raudenska, V Adam, R Kizek… - PloS one, 2014 - journals.plos.org
Metallothionein (MT) has been extensively investigated as a molecular marker of various
types of cancer. In spite of the fact that numerous reviews have been published in this field …