Exosome-mediated metastasis: communication from a distance

I Wortzel, S Dror, CM Kenific, D Lyden - Developmental cell, 2019 - cell.com
Metastasis, a critical phase of tumor progression, remains a primary challenge in treating
cancer and a major cause of cancer mortality. Cell-cell communication via extracellular …

Nanochemistry advancing photon conversion in rare-earth nanostructures for theranostics

R Lv, M Raab, Y Wang, J Tian, J Lin… - Coordination Chemistry …, 2022 - Elsevier
Rare-earth (RE) doped nanoparticles show unique features of photon conversion from an
incident wavelength to a more suitable wavelength at an intended biological site, thus …

Collagenase nanoparticles enhance the penetration of drugs into pancreatic tumors

A Zinger, L Koren, O Adir, M Poley, M Alyan, Z Yaari… - ACS …, 2019 - ACS Publications
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC)
limits drug penetration into the tumor and is associated with poor prognosis. Here, we …

Modified bovine milk exosomes for doxorubicin delivery to triple-negative breast cancer cells

J Pullan, K Dailey, S Bhallamudi, L Feng… - ACS applied bio …, 2022 - ACS Publications
Biological nanoparticles, such as exosomes, offer an approach to drug delivery because of
their innate ability to transport biomolecules. Exosomes are derived from cells and an …

Advances of nanomedicines in breast cancer metastasis treatment targeting different metastatic stages

W Yu, C Hu, H Gao - Advanced Drug Delivery Reviews, 2021 - Elsevier
Breast cancer is the most common tumor in women, and the metastasis further increases the
malignancy with extremely high mortality. However, there is almost no effective method in …

[HTML][HTML] Engineering tumor-targeting nanoparticles as vehicles for precision nanomedicine

A Gonda, N Zhao, JV Shah, HR Calvelli, H Kantamneni… - Med one, 2019 - ncbi.nlm.nih.gov
As a nascent and emerging field that holds great potential for precision oncology,
nanotechnology has been envisioned to improve drug delivery and imaging capabilities …

Targeting integrins in cancer nanomedicine: applications in cancer diagnosis and therapy

PH Wu, AE Opadele, Y Onodera, JM Nam - Cancers, 2019 - mdpi.com
Due to advancements in nanotechnology, the application of nanosized materials
(nanomaterials) in cancer diagnostics and therapeutics has become a leading area in …

Synthesis and characterization of nanometer-sized liposomes for encapsulation and microRNA transfer to breast cancer cells

H Lujan, WC Griffin, JH Taube… - International journal of …, 2019 - Taylor & Francis
Introduction: The use of liposomes as a drug delivery carrier (DDC) for the treatment of
various diseases, especially cancer, is rapidly increasing, requiring more stringent …

Recent progress in nanocarrier-based drug delivery systems for antitumour metastasis

S Peng, X Yuan, H Li, Y Wei, B Zhou, G Ding… - European Journal of …, 2023 - Elsevier
Tumour metastasis is one of the major factors leading to poor prognosis as well as lower
survival among cancer patients. A number of studies investigating the inhibition of tumour …

Ultrabright near-infrared fluorescent DNA frameworks for near-single-cell cancer imaging

X Liu, B Shi, Y Gao, S Zhu, Q Yan, X Liu, J Shi, Q Li… - Nature …, 2024 - nature.com
Cancer imaging approaching single-cell levels is highly desirable for studying in vivo cell
migration and cancer metastasis. However, current imaging probes struggle to …