Recent advancements of coumarin-based anticancer agents: An up-to-date review

T Al-Warhi, A Sabt, EB Elkaeed, WM Eldehna - Bioorganic Chemistry, 2020 - Elsevier
Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

Antioxidant activity of coumarins and their metal complexes

L Todorov, L Saso, I Kostova - Pharmaceuticals, 2023 - mdpi.com
Ubiquitously present in plant life, coumarins, as a class of phenolic compounds, have
multiple applications—in everyday life, in organic synthesis, in medicine and many others …

Structure activity relationship (SAR) and anticancer activity of pyrrolidine derivatives: Recent developments and future prospects (A review)

AA Bhat, I Singh, N Tandon, R Tandon - European Journal of Medicinal …, 2023 - Elsevier
Pyrrolidine molecules are a significant class of synthetic and natural plant metabolites,
which show the diversity of pharmacological activities. An extensive variety of synthetic …

[HTML][HTML] New coumarin derivative with potential antioxidant activity: Synthesis, DNA binding and in silico studies (Docking, MD, ADMET)

S Kecel-Gunduz, Y Budama-Kilinc, B Bicak… - Arabian Journal of …, 2023 - Elsevier
Abstract A new coumarin derivative, 7-((8-(4-benzylpiperidin-1-yl) octyl) oxy)-4-methyl-2H-
chromen-2-one (C3), was synthesized by two-step alkylation reaction of 7-hydroxy-4-methyl …

Natural product coumarins: biological and pharmacological perspectives

MI Hussain, QA Syed, MNK Khattak, B Hafez… - Biologia, 2019 - Springer
Plants produce and release a vast variety of secondary metabolites with diversified
functions, and possess ecological, toxicological and biological effects that mimic the …

[HTML][HTML] Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok… - RSC Medicinal …, 2024 - ncbi.nlm.nih.gov
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

LC-ESI-QTOF-MS/MS characterisation of phenolics in herbal tea infusion and their antioxidant potential

O Chou, A Ali, V Subbiah, CJ Barrow, FR Dunshea… - Fermentation, 2021 - mdpi.com
Ginger (Zingiber officinale R.), lemon (Citrus limon L.) and mint (Mentha sp.) are commonly
consumed medicinal plants that have been of interest due to their health benefits and …

[HTML][HTML] Antioxidant and anti-inflammatory properties of marmelosin from Bael (Aegle marmelos L.); Inhibition of TNF-α mediated inflammatory/tumor markers

H Pynam, SM Dharmesh - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Oxidative stress and inflammation are important critical factors that are implicated in almost
all life style disorders such as diabetes, cardiovascular disease, ulcer and cancer. Current …

Coumarins from Rutaceae: Chemical diversity and biological activities

CMS Junior, SMC Silva, EM Sales, E da Silva Velozo… - Fitoterapia, 2023 - Elsevier
Rutaceae is a family expressed by approximately 2100 species distributed in 154 genera
widespread in tropical and temperate regions of Australasia, America, and South Africa …

Phenolic profile, antioxidant, anticholinesterase, and anti-tyrosinase activities of the various extracts of Ferula elaeochytris and Sideritis stricta

E Deveci, G Tel-Çayan, ME Duru - International journal of food …, 2018 - Taylor & Francis
In this study, the antioxidant, anticholinesterase, and anti-tyrosinase properties of (hexane,
acetone, methanol, and water) extracts of Ferula elaeochytris and Sideritis stricta were …