[HTML][HTML] Aggression, social stress, and the immune system in humans and animal models

A Takahashi, ME Flanigan, BS McEwen… - Frontiers in Behavioral …, 2018 - frontiersin.org
Social stress can lead to the development of psychological problems ranging from
exaggerated anxiety and depression to antisocial and violence-related behaviors …

Is serotonin an upper or a downer? The evolution of the serotonergic system and its role in depression and the antidepressant response

PW Andrews, A Bharwani, KR Lee, M Fox… - Neuroscience & …, 2015 - Elsevier
The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …

Cytokines and major depression

OJG Schiepers, MC Wichers, M Maes - Progress in Neuro …, 2005 - Elsevier
In the research field of psychoneuroimmunology, accumulating evidence has indicated the
existence of reciprocal communication pathways between nervous, endocrine and immune …

[HTML][HTML] Comparison of bacterial lipopolysaccharide-induced sickness behavior in rodents and humans: Relevance for symptoms of anxiety and depression

J Lasselin, M Schedlowski, B Karshikoff… - Neuroscience & …, 2020 - Elsevier
Increasing evidence from animal and human studies suggests that inflammation may be
involved in mood disorders. Sickness behavior and emotional changes induced by …

Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function

S Hosseini, E Wilk, K Michaelsen-Preusse… - Journal of …, 2018 - Soc Neuroscience
Acute influenza infection has been reported to be associated with neurological symptoms.
However, the long-term consequences of an infection with neurotropic and non-neurotropic …

Cytokines and cognition—the case for a head‐to‐toe inflammatory paradigm

CJ Wilson, CE Finch, HJ Cohen - Journal of the American …, 2002 - Wiley Online Library
The brain is not only immunologically active of its own accord, but also has complex
peripheral immune interactions. Given the central role of cytokines in …

Association of inflammation and cognition in the elderly: a systematic review and meta-analysis

S Leonardo, F Fregni - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Background The development of mild cognitive impairment (MCI) and Alzheimer's disease
(AD) may be associated with an inflammatory process. Inflammatory cytokines may be a …

DNA methylation: a mechanism for embedding early life experiences in the genome

M Szyf, J Bick - Child development, 2013 - Wiley Online Library
Although epidemiological data provide evidence that early life experience plays a critical
role in human development, the mechanism of how this works remains in question. Recent …

Depression, stress and immunological activation: the role of cytokines in depressive disorders

TJ Connor, BE Leonard - Life sciences, 1998 - Elsevier
Traditionally, both stress and depression have been associated with impaired immune
function and increased susceptibility to infectious and neoplastic disease. However over the …

Role of serotonin in the immune system and in neuroimmune interactions

R Mössner, KP Lesch - Brain, behavior, and immunity, 1998 - Elsevier
Serotonin (5-HT) is one of the most extensively studied neurotransmitters of the central
nervous system. 5-HT is, however, also present in a variety of peripheral tissues including in …