Primary brain tumors account for~ 1% of new cancer cases and~ 2% of cancer deaths in the
United States; however, they are the most commonly occurring solid tumors in children …

Gliomas are the most common primary intracranial tumor, representing 81% of malignant
brain tumors. Although relatively rare, they cause significant mortality and morbidity …

To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-
genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence …

Background Biological aging estimators derived from DNA methylation data are heritable
and correlate with morbidity and mortality. Consequently, identification of genetic and …

Background The prediction of clinical behavior, response to therapy, and outcome of
infiltrative glioma is challenging. On the basis of previous studies of tumor biology, we …

Genome-wide association studies (GWAS) provide an agnostic approach for investigating
the genetic basis of complex diseases. In oncology, GWAS of nearly all common …

Glioblastoma is the most common and lethal primary malignant brain tumor in adults.
Patients die from recurrent tumors that have become resistant to therapy. New strategies are …

Periodontal disease, which includes gingivitis and periodontitis, is highly prevalent in adults
and disease severity increases with age. The relationship between periodontal disease and …

Gliomas are one of the most common types of primary brain tumors and have remained
particularly challenging to treat. This review illustrates a multidisciplinary approach to the …

Background CBTRUS is currently the only population-based site-specific registry in the US
that works in partnership with a public cancer surveillance organization, the CDC's NPCR …