The novel regulatory role of lnc RNA‐mi RNA‐mRNA axis in cardiovascular diseases

Y Huang - Journal of cellular and molecular medicine, 2018 - Wiley Online Library
Long noncoding RNA s (lnc RNA s) are RNA s longer than 200 nt in length that are
characterized by low levels of sequence conservation and expression; lnc RNA s modulate …

[HTML][HTML] Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment

Z Sun, S Yang, Q Zhou, G Wang, J Song, Z Li, Z Zhang… - Molecular cancer, 2018 - Springer
Exosomes are extracellular vesicles released by many cell types and have been attributed
for their roles in many diseases including cancer. Exosomes secreted by tumor cells and …

[HTML][HTML] MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

N Amodio, L Raimondi, G Juli, MA Stamato… - Journal of hematology & …, 2018 - Springer
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

The emerging role of exosome-derived non-coding RNAs in cancer biology

Q Fan, L Yang, X Zhang, X Peng, S Wei, D Su, Z Zhai… - Cancer letters, 2018 - Elsevier
Exosomes are a new means of intercellular information exchange that have aroused great
research interest. Long neglected in research, exosomes were deemed nonfunctional …

[HTML][HTML] Role of extracellular vesicles in tumour microenvironment

SC Tao, SC Guo - Cell Communication and Signaling, 2020 - Springer
In recent years, it has been demonstrated that extracellular vesicles (EVs) can be released
by almost all cell types, and detected in most body fluids. In the tumour microenvironment …

[HTML][HTML] LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214

Y Chen, H Du, L Bao, W Liu - Cancer biology & medicine, 2018 - ncbi.nlm.nih.gov
Objective: Emerging evidence indicates that long non-coding RNAs (lncRNAs) are critical in
carcinogenesis and progression of ovarian cancer. This study aimed to explore the functions …

[HTML][HTML] LncRNA SNHG15 regulates EGFR-TKI acquired resistance in lung adenocarcinoma through sponging miR-451 to upregulate MDR-1

J Huang, B Pan, G Xia, J Zhu, C Li, J Feng - Cell death & disease, 2020 - nature.com
Lung adenocarcinoma (LUAD) is the main component of non-small-cell lung cancer
(NSCLC) and causes a great health concern globally. The top priority of LUAD treatment is …

Long noncoding RNA CERS6‐AS1 functions as a malignancy promoter in breast cancer by binding to IGF2BP3 to enhance the stability of CERS6 mRNA

G Bao, J Huang, W Pan, X Li, T Zhou - Cancer medicine, 2020 - Wiley Online Library
Breast cancer (BC) leads to the highest mortality in women worldwide, characterized by
inevitable proliferation and metastasis of BC cells. Mounting evidence confirm that lncRNAs …

Exosome-mediated transfer of miR-1290 promotes cell proliferation and invasion in gastric cancer via NKD1

J Huang, M Shen, M Yan, Y Cui, Z Gao… - Acta biochimica et …, 2019 - academic.oup.com
Currently, exosomes rich in RNAs and proteins are regarded as vital mediators of
intercellular communication. Here, we aimed to explore the effects of exosomal miR-1290 in …

[HTML][HTML] The long noncoding RNA HOTAIR in breast cancer: does autophagy play a role?

E Pawłowska, J Szczepanska, J Blasiak - International journal of …, 2017 - mdpi.com
HOTAIR (HOX transcript antisense RNA) plays a critical role in chromatin dynamics through
the interaction with histone modifiers resulting in transcriptional gene silencing. The …