Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment

W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …

Poxviruses and the immune system: Implications for monkeypox virus

A Saghazadeh, N Rezaei - International Immunopharmacology, 2022 - Elsevier
Poxviruses (PXVs) are mostly known for the variola virus, being the cause of smallpox;
however, re-emerging PXVs have also shown a great capacity to develop outbreaks of pox …

Challenges of delirium management in patients with traumatic brain injury: from pathophysiology to clinical practice

SW Roberson, MB Patel, W Dabrowski… - Current …, 2021 - benthamdirect.com
Traumatic brain injury (TBI) can initiate a very complex disease of the central nervous
system (CNS), starting with the primary pathology of the inciting trauma and subsequent …

Viral SERPINS—A Family of Highly Potent Immune-Modulating Therapeutic Proteins

K Varkoly, R Beladi, M Hamada, G McFadden, J Irving… - Biomolecules, 2023 - mdpi.com
Serine protease inhibitors, SERPINS, are a highly conserved family of proteins that regulate
serine proteases in the central coagulation and immune pathways, representing 2–10% of …

The Brain-gut Axis-where are we now and how can we Modulate these Connections?

W Dabrowski, D Siwicka-Gieroba… - Current …, 2021 - benthamdirect.com
A traumatic brain injury (TBI) initiates an inflammatory response with molecular cascades
triggered by the presence of necrotic debris, including damaged myelin, hemorrhages and …

The role of astrogliosis in formation of the syrinx in spinal cord injury

JM Kwiecien, W Dąbrowski, JR Yaron… - Current …, 2021 - ingentaconnect.com
A massive localized trauma to the spinal cord results in complex pathologic events driven by
necrosis and vascular damage which in turn leads to hemorrhage and edema. Severe …

Barriers to axonal regeneration after spinal cord injury: a current perspective

JM Kwiecien - Neural Regeneration Research, 2022 - journals.lww.com
Regeneration of long axons after the spinal cord injury (SCI) will benefit patients with
extensive traumatic damage to the white matter pathways who experience intolerable …

Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling

JR Yaron, L Zhang, Q Guo, EA Awo, M Burgin… - Pharmaceutics, 2020 - mdpi.com
Complex dermal wounds represent major medical and financial burdens, especially in the
context of comorbidities such as diabetes, infection and advanced age. New approaches to …

[HTML][HTML] Serine proteases and chemokines in neurotrauma: new targets for immune modulating therapeutics in spinal cord injury

RN Beladi, KS Varkoly, L Schutz, L Zhang… - Current …, 2021 - ncbi.nlm.nih.gov
Progressive neurological damage after brain or spinal cord trauma causes loss of motor
function and treatment is very limited. Clotting and hemorrhage occur early after spinal cord …

Early CSF biomarkers and late functional outcomes in spinal cord injury. A Pilot Study

R Capirossi, B Piunti, M Fernández, E Maietti… - International Journal of …, 2020 - mdpi.com
Although, biomarkers are regarded as an important tool for monitoring injury severity and
treatment efficacy, and for predicting clinical evolution in many neurological diseases and …