The failure of preclinical research to advance successful candidate medications in
psychiatry has created a paradigmatic crisis in psychiatry. The Research Domain Criteria …

A large focus of modern neuroscience has revolved around preselected brain regions of
interest based on prior studies. While there are reasons to focus on brain regions implicated …

A central theory of basal ganglia function is that striatal neurons expressing the D1 and D2
dopamine receptors exert opposing brain-wide influences. However, the causal influence of …

Although the connectivity of hippocampal circuits has been extensively studied, the way in
which these connections give rise to large-scale dynamic network activity remains unknown …

Defining the large-scale behavior of brain circuits with cell type specificity is a major goal of
neuroscience. However, neuronal circuit diagrams typically draw upon anatomical and …

In preclinical studies, implanted electrodes can cause severe degradation of MRI images
and hence are seldom used for chronic studies employing functional magnetic resonance …

Purpose To propose a novel compressed sensing (CS) high spatial resolution functional
MRI (fMRI) method and demonstrate the advantages and limitations of using CS for high …

The investigation of the functional connectivity of precise neural circuits across the entire
intact brain can be achieved through optogenetic functional magnetic resonance imaging …

A large number of fMRI studies have shown that the temporal dynamics of evoked BOLD
responses can be highly heterogeneous. Failing to model heterogeneous responses in …

Understanding how stem cell‐derived neurons functionally integrate into the brain upon
transplantation has been a long sought‐after goal of regenerative medicine. However …