Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process

A Latka, B Maciejewska, G Majkowska-Skrobek… - Applied microbiology …, 2017 - Springer
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition
and adsorption to the cell surface. The irreversible adherence followed by genome material …

Applications of bacteriophages versus phage enzymes to combat and cure bacterial infections: an ambitious and also a realistic application?

B Maciejewska, T Olszak, Z Drulis-Kawa - Applied microbiology and …, 2018 - Springer
Bacteriophages (phages) are viruses that infect bacteria. The “predator–prey” interactions
are recognized as a potentially effective way to treat infections. Phages, as well as phage …

Endolysins as emerging alternative therapeutic agents to counter drug-resistant infections

VS Gondil, K Harjai, S Chhibber - International journal of antimicrobial …, 2020 - Elsevier
Endolysins are the lytic products of bacteriophages which play a specific role in the release
of phage progeny by degrading the peptidoglycan of the host bacterium. In the light of …

Bacteriophages of Klebsiella spp., their diversity and potential therapeutic uses

WP Herridge, P Shibu, J O'Shea… - Journal of medical …, 2020 - microbiologyresearch.org
Klebsiella spp. are commensals of the human microbiota, and a leading cause of
opportunistic nosocomial infections. The incidence of multidrug resistant (MDR) strains of …

Gram-negative bacterial lysins

C Ghose, CW Euler - Antibiotics, 2020 - mdpi.com
Antibiotics have had a profound impact on human society by enabling the eradication of
otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid …

Phage lysins for fighting bacterial respiratory infections: a new generation of antimicrobials

R Vázquez, E García, P García - Frontiers in immunology, 2018 - frontiersin.org
Lower respiratory tract infections and tuberculosis are responsible for the death of about 4.5
million people each year and are the main causes of mortality in children under 5 years of …

[HTML][HTML] Bacteriophage-encoded enzymes destroying bacterial cell membranes and walls, and their potential use as antimicrobial agents

Ł Grabowski, K Łepek, M Stasiłojć… - Microbiological …, 2021 - Elsevier
Appearance of pathogenic bacteria resistant to most, if not all, known antibiotics is currently
one of the most significant medical problems. Therefore, development of novel antibacterial …

Bacteriophage-derived endolysins to target gram-negative bacteria

WCB Lai, X Chen, MKY Ho, J Xia, SSY Leung - International Journal of …, 2020 - Elsevier
Bacteriophage-encoded endolysins (lysins) have emerged as a novel class of antibacterial
agents to combat the surging antibiotic resistance. Lysins have specific structures and …

Clostridioides difficile phage biology and application

J Heuler, LC Fortier, X Sun - FEMS Microbiology Reviews, 2021 - academic.oup.com
Clostridium difficile, now reclassified as Clostridioides difficile, is the causative agent of C.
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …

A comprehensive review of the applications of bacteriophage-derived endolysins for foodborne bacterial pathogens and food safety: recent advances, challenges, and …

FM Khan, JH Chen, R Zhang, B Liu - Frontiers in Microbiology, 2023 - frontiersin.org
Foodborne diseases are caused by food contaminated by pathogenic bacteria such as
Escherichia coli, Salmonella, Staphylococcus aureus, Listeria monocytogenes …