Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Autophagy is well-known as an internal catabolic process that is evolutionarily conserved
and performs the key biological function in maintaining cellular homeostasis. It is tightly …

A long-standing hypothesis proposes that certain RNA (s) must exhibit structural roles in
microtubule assembly. Here, we identify a long noncoding RNA (TubAR) that is highly …

Background Papillary thyroid carcinoma (PTC) accounts for about 85% of thyroid cancer
cases. Transmembrane protein 252 (TMEM252) is a gene encoding a transmembrane …

Distant metastasis is responsible for high mortality in most cancer cases and the lung is one
of the most common target organs, severely affecting the quality of daily life and overall …

Breast cancer (BC) is the most common malignant tumor in women, and the majority of BC-
related deaths are due to tumor metastasis. There is emerging evidence for the role of long …

Cancer is a group of diseases marked by unchecked cell proliferation and the ability for the
disease to metastasize to different body areas. Enhancements in treatment and early …

Type 1 insulin-like growth factor receptor (IGF1R) plays an important role in cancer,
however, posttranscriptional regulation such as N 6-methyladenosine (m6A) of IGF1R …

Simple Summary NEDD4 family members have been investigated to play contributory role in
carcinogenesis. In this review article, we have exclusively focused on the regulation and …

Mammalian E3 ubiquitin ligases have emerged in recent years as critical regulators of
cellular homeostasis due to their roles in targeting substrate proteins for ubiquitination and …