All about running: synaptic plasticity, growth factors and adult hippocampal neurogenesis

C Vivar, MC Potter, H van Praag - Neurogenesis and neural plasticity, 2013 - Springer
Accumulating evidence from animal and human research shows exercise benefits learning
and memory, which may reduce the risk of neurodegenerative diseases, and could delay …

Effects of diabetes on hippocampal neurogenesis: links to cognition and depression

N Ho, MS Sommers, I Lucki - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Diabetes often leads to a number of complications involving brain function, including
cognitive decline and depression. In addition, depression is a risk factor for developing …

Lifelong bilingualism maintains white matter integrity in older adults

G Luk, E Bialystok, FIM Craik… - Journal of Neuroscience, 2011 - Soc Neuroscience
Previous research has shown that bilingual speakers have higher levels of cognitive control
than comparable monolinguals, especially at older ages. The present study investigates a …

Running is the neurogenic and neurotrophic stimulus in environmental enrichment

T Kobilo, QR Liu, K Gandhi, M Mughal… - Learning & …, 2011 - learnmem.cshlp.org
Environmental enrichment (EE) increases dentate gyrus (DG) neurogenesis and brain-
derived neurotrophic factor (BDNF) levels. However, running is considered an element of …

[HTML][HTML] Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice

WH Oliveira, AK Nunes, MER França, LA Santos… - Brain research, 2016 - Elsevier
The aim of the present study was to analyze the action of metformin on short-term memory,
glial cell activation and neuroinflammation caused by experimental diabetic encephalopathy …

Effects of diet on brain plasticity in animal and human studies: mind the gap

T Murphy, GP Dias, S Thuret - Neural plasticity, 2014 - Wiley Online Library
Dietary interventions have emerged as effective environmental inducers of brain plasticity.
Among these dietary interventions, we here highlight the impact of caloric restriction (CR: a …

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

P Bekinschtein, CA Oomen, LM Saksida… - Seminars in cell & …, 2011 - Elsevier
Adult-generated neurons in the dentate gyrus of the hippocampus have been the focus of
many studies concerned with learning and memory (L&M). It has been shown that …

Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment

NE Everds, PW Snyder, KL Bailey… - Toxicologic …, 2013 - journals.sagepub.com
Stress often occurs during toxicity studies. The perception of sensory stimuli as stressful
primarily results in catecholamine release and activation of the hypothalamic–pituitary …

Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease

J Beauquis, P Pavía, C Pomilio, A Vinuesa… - Experimental …, 2013 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that affects neurons and glial cells
and leads to dementia. Growing evidence shows that glial changes may precede neuronal …

Environmental enrichment and mouse models: Current perspectives

K Bayne - Animal models and experimental medicine, 2018 - Wiley Online Library
The provision of environmental enrichment to numerous species of laboratory animals is
generally considered routine husbandry. However, mouse enrichment has proven to be very …