Background The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all
over the world, posing a great pressure on critical care resources due to large number of …

Life expectancy is increasing and so is the prevalence of age-related non-communicable
diseases (NCDs). Consequently, older people and patients present with multi-morbidities …

Background On the basis of low-quality evidence, international critical care nutrition
guidelines recommend a wide range of protein doses. The effect of delivering high-dose …

The importance of the interplay between inflammation and nutrition has generated much
interest in recent times. Inflammation has been identified as a key driver for disease-related …

Personalization of ICU nutrition is essential to future of critical care. Recommendations from
American/European guidelines and practice suggestions incorporating recent literature are …

Background The optimal protein dose in critical illness is unknown. We aim to conduct a
systematic review of randomized controlled trials (RCTs) to compare the effect of higher …

Background Medical nutrition therapy may be associated with clinical outcomes in critically
ill patients with prolonged intensive care unit (ICU) stay. We wanted to assess nutrition …

In 1747, an important milestone in the history of clinical research was set, as the Scottish
surgeon James Lind conducted the first randomized controlled trial. Lind was interested in …

The COVID-19 pandemics has created unprecedented challenges and threats to patients
and healthcare systems worldwide. Acute respiratory complications that require intensive …

Background & aims The degradation of muscle mass and loss of functional proteins due to
catabolism are associated with adverse outcomes in critically ill patients. While an adequate …