Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

[HTML][HTML] Recent developments in the high-throughput separation of biologically active chiral compounds via high performance liquid chromatography

C De Luca, S Felletti, FA Franchina, D Bozza… - … of Pharmaceutical and …, 2024 - Elsevier
Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Nonadditivity and nonlinearity of mobile and stationary zone mass transfer resistances in chromatography

B Huygens, C Venditti, A Adrover… - Analytical Chemistry, 2023 - ACS Publications
Using a two-zone moment analysis (TZMA) method based on Brenner's generalized
dispersion theory for two-dimensional (2D) and three-dimensional (3D) periodic media, we …

Understanding the transition from high-selective to high-efficient chiral separations by changing the organic modifier with zwitterionic-teicoplanin chiral stationary …

S Felletti, C De Luca, G Mazzoccanti… - Analytical …, 2023 - ACS Publications
The retention behavior of small molecules and N-protected amino acids on a zwitterionic
teicoplanin chiral stationary phase (CSP), prepared on superficially porous particles (SPPs) …

[HTML][HTML] Moment analysis for predicting effective transport properties in hierarchical retentive porous media

C Venditti, B Huygens, G Desmet, A Adrover - Journal of Chromatography A, 2023 - Elsevier
We report on a new homogenization approach to solve, with drastically improved speed and
accuracy, the general advection-diffusion equation in hierarchical porous media with …

[HTML][HTML] Dimethyl carbonate as a green alternative to acetonitrile in reversed-phase liquid chromatography. Part I: Separation of small molecules

S Felletti, M Spedicato, D Bozza, C De Luca… - … of Chromatography A, 2023 - Elsevier
Nowadays, environmental problems are drawing the attention of governments and
international organisations, which are therefore encouraging the transition to green …

[HTML][HTML] An alternative general model for the effective longitudinal diffusion in chromatographic beds filled with ordered porous particles

A Adrover, C Venditti, G Desmet - Journal of Chromatography A, 2024 - Elsevier
The two-zone moment-analysis method for the determination of the dispersion tensor in
hierarchical retentive porous media has been adopted to compute and model the effective …

Investigation of retention behavior of natural cannabinoids on differently substituted polysaccharide-based chiral stationary phases under reversed-phase liquid …

C De Luca, A Buratti, W Umstead, P Franco… - … of Chromatography A, 2022 - Elsevier
The growing popularity of cannabis products and recent legalization of cannabis for
recreational purposes have contributed to the increase of the demand for analytical methods …

Review of recent insights in the measurement and modelling of the B-term dispersion and related mass transfer properties in liquid chromatography

G Desmet, K Broeckhoven, S Deridder… - Analytica Chimica Acta, 2022 - Elsevier
In this contribution, we review the recent literature relating to the measurement and
modelling of all diffusion-dominated processes contributing to the efficiency of a …

A perspective on enantioselective chromatography by comparing ultra-high performance supercritical fluid chromatography and normal-phase liquid chromatography …

G Mazzoccanti, S Manetto, A Ciogli, C Villani… - TrAC Trends in …, 2022 - Elsevier
Since their discovery, the Pirkle-type chiral stationary phases, and in particular the Whelk-
O1, have been used in a large number of applications and theoretical studies. Although they …