Ochratoxin A: molecular interactions, mechanisms of toxicity and prevention at the molecular level

T Kőszegi, M Poór - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health
risks. The focus of the present review is on the molecular and cellular interactions of OTA. In …

Toxicity, metabolism, and impact of mycotoxins on humans and animals

HS Hussein, JM Brasel - Toxicology, 2001 - Elsevier
The worldwide contamination of foods and feeds with mycotoxins is a significant problem.
Mycotoxins are secondary metabolites of molds that have adverse effects on humans …

Toxicokinetics and toxicodynamics of ochratoxin A, an update

D Ringot, A Chango, YJ Schneider… - Chemico-biological …, 2006 - Elsevier
Ochratoxin A (OTA) is a mycotoxin produced by fungi of two genera: Penicillium and
Aspergillus. OTA has been shown to be nephrotoxic, hepatotoxic, teratogenic and …

Ochratoxin A: the continuing enigma

E O'Brien, DR Dietrich - Critical reviews in toxicology, 2005 - Taylor & Francis
The mycotoxin ochratoxin A (OTA) has been linked to the genesis of several disease states
in both animals and humans. It has been described as nephrotoxic, carcinogenic …

Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathways

K Doi, K Uetsuka - International journal of molecular sciences, 2011 - mdpi.com
Among many mycotoxins, T-2 toxin, macrocyclic trichothecenes, fumonisin B1 (FB1) and
ochratochin A (OTA) are known to have the potential to induce neurotoxicity in rodent …

Immunotoxic activity of ochratoxin A

L Al‐Anati, E Petzinger - Journal of veterinary pharmacology …, 2006 - Wiley Online Library
Ochratoxin A (OTA) is an immunosuppressant fungal compound, produced by toxigenic
species of Aspergillus and Penicillium fungi in a wide variety of climates and geographical …

Acute neurotoxic effects of the fungal metabolite ochratoxin-A

V Sava, O Reunova, A Velasquez, R Harbison… - Neurotoxicology, 2006 - Elsevier
Ochratoxin-A (OTA) is a fungal metabolite with potential toxic effects on the central nervous
system that have not yet been fully characterized. OTA has complex mechanisms of action …

Effects of curcumin on performance, antioxidation, intestinal barrier and mitochondrial function in ducks fed corn contaminated with ochratoxin A

D Ruan, WC Wang, CX Lin, AM Fouad, W Chen… - Animal, 2019 - cambridge.org
Curcumin has been attributed with antioxidant, anti-inflammatory, antibacterial activities, and
has shown highly protective effects against enteropathogenic bacteria and mycotoxins …

Detoxification of cancerogenic compounds by lactic acid bacteria strains

Z Lili, W Junyan, Z Hongfei, Z Baoqing… - Critical reviews in food …, 2018 - Taylor & Francis
Carcinogens in food are an important issue that threat people's health right now. Lactic acid
bacteria (LAB) strains as well-known probiotics have shown numerous perspectives in being …

Evaluation of in vitro mitochondrial toxicity assays and physicochemical properties for prediction of organ toxicity using 228 pharmaceutical drugs

P Rana, MD Aleo, M Gosink, Y Will - Chemical research in …, 2018 - ACS Publications
Mitochondrial toxicity has been shown to contribute to a variety of organ toxicities such as
liver, cardiac, and kidney. In the past decades, two high-throughput applicable screening …