Outpatient treatment of low‐risk pulmonary embolism in the era of direct oral anticoagulants: a systematic review

BC Maughan, L Frueh, MS McDonagh… - Academic …, 2021 - Wiley Online Library
Background Clinical guidelines have supported outpatient treatment of low‐risk pulmonary
embolism (PE) since 2014, but adoption of this practice has been slow. Direct oral …

Direct oral anticoagulant drugs: On the treatment of cancer-related venous thromboembolism and their potential anti-neoplastic effect

F Grandoni, L Alberio - Cancers, 2019 - mdpi.com
Cancer patients develop a hypercoagulable state with a four-to seven-fold higher
thromboembolic risk compared to non-cancer patients. Thromboembolic events can precede …

Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial

FA Klok, G Toenges, AC Mavromanoli… - The Lancet …, 2021 - thelancet.com
Background Current guidelines recommend a risk-adjusted treatment strategy for the
management of acute pulmonary embolism. This is a particular patient category for whom …

Acute pulmonary embolism: contemporary approach to diagnosis, risk-stratification, and management

T Tak, S Karturi, U Sharma, L Eckstein… - … Journal of Angiology, 2019 - thieme-connect.com
Pulmonary embolism (PE) affects over 300,000 individuals each year in the United States
and is associated with substantial morbidity and mortality. Improvements in the diagnostic …

Intravenous thrombolysis in acute ischemic stroke after dabigatran reversal with idarucizumab–a case report

JS Mutzenbach, S Pikija, F Otto… - Annals of clinical …, 2016 - Wiley Online Library
Much excitement has been generated with the approval of idarucizumab, a humanized
monoclonal antigen‐binding antibody fragment that is capable of reversing the …

[HTML][HTML] Nuevos anticoagulantes orales: actualización

A Berkovits, D Mezzano - Revista chilena de cardiología, 2017 - SciELO Chile
Los anticoagulantes orales clásicos del tipo cumarinas han estado disponibles para uso
clínico por más de medio siglo. Tienen gran eficacia para tratar o prevenir trombosis y …

Effects of oral anticoagulant therapy in patients with pulmonary diseases

J Lai, S Feng, S Xu, X Liu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Background To evaluate the effect of oral anticoagulants (OACs) therapy, including vitamin
K antagonist (VKA) and direct oral anticoagulants (DOAC) in patients with pulmonary …

Anticoagulation in deep venous thrombosis: current trends in the era of non-vitamin K antagonists oral anticoagulants

PE Papakonstantinou, C Tsioufis… - Current …, 2020 - ingentaconnect.com
Anticoagulation therapy is the cornerstone of treatment in acute vein thrombosis (DVT) and it
aims to reduce symptoms, thrombus extension, DVT recurrences, and mortality. The …

Factor Xa inhibition for the treatment of venous thromboembolism associated with cancer: a meta-analysis of the randomised controlled trials

AC Murphy, AN Koshy, O Farouque, B Yeo… - Heart, Lung and …, 2022 - Elsevier
Background Venous thromboembolism (VTE) is a common cause of morbidity and mortality
in cancer patients. Until recently, guidelines recommended the use of low-molecular weight …

Direct oral anticoagulants in the treatment of pulmonary embolism

JB Eldredge, AC Spyropoulos - Current medical research and …, 2018 - Taylor & Francis
Objective: The objective of this review is to examine the management strategies for
pulmonary embolism (PE) with an emphasis of the role of direct oral anticoagulants …