Swine influenza A viruses and the tangled relationship with humans

TK Anderson, J Chang… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Influenza A viruses (IAVs) are the causative agents of one of the most important viral
respiratory diseases in pigs and humans. Human and swine IAV are prone to interspecies …

Adaptation of human influenza viruses to swine

DS Rajao, AL Vincent, DR Perez - Frontiers in veterinary Science, 2019 - frontiersin.org
A large diversity of influenza A viruses (IAV) within the H1N1/N2 and H3N2 subtypes
circulates in pigs globally, with different lineages predominating in specific regions of the …

Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations

K Ganti, A Bagga, S Carnaccini, LM Ferreri… - Nature …, 2022 - nature.com
Influenza A virus (IAV) genetic exchange through reassortment has the potential to
accelerate viral evolution and has played a critical role in the generation of multiple …

Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential

A Markin, G Ciacci Zanella, ZW Arendsee… - PLoS …, 2023 - journals.plos.org
The 2009 H1N1 pandemic (pdm09) lineage of influenza A virus (IAV) crosses interspecies
barriers with frequent human-to-swine spillovers each year. These spillovers reassort and …

Fitness determinants of influenza A viruses

EF Griffin, SM Tompkins - Viruses, 2023 - mdpi.com
Influenza A (IAV) is a major human respiratory pathogen that causes illness,
hospitalizations, and mortality annually worldwide. IAV is also a zoonotic pathogen with a …

Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States

DS Rajao, TK Anderson, P Kitikoon, J Stratton… - Virology, 2018 - Elsevier
Several lineages of influenza A viruses (IAV) currently circulate in North American pigs.
Genetic diversity is further increased by transmission of IAV between swine and humans and …

Detection of live attenuated influenza vaccine virus and evidence of reassortment in the US swine population

A Sharma, MA Zeller, G Li, KM Harmon… - Journal of …, 2020 - journals.sagepub.com
Influenza vaccines historically have been multivalent, whole virus inactivated products. The
first bivalent, intranasal, live attenuated influenza vaccine (LAIV; Ingelvac Provenza), with …

Human-to-swine introductions and onward transmission of 2009 H1N1 pandemic influenza viruses in Brazil

DM Junqueira, C Tochetto, TK Anderson… - Frontiers in …, 2023 - frontiersin.org
Introduction Once established in the human population, the 2009 H1N1 pandemic virus
(H1N1pdm09) was repeatedly introduced into swine populations globally with subsequent …

The epidemiology of swine influenza

Y Li, I Robertson - Animal diseases, 2021 - Springer
Globally swine influenza is one of the most important diseases of the pig industry, with
various subtypes of swine influenza virus co-circulating in the field. Swine influenza can not …

[HTML][HTML] Gradual adaptation of animal influenza a viruses to human-type sialic acid receptors

M Liu, FJM van Kuppeveld, CAM de Haan… - Current Opinion in …, 2023 - Elsevier
Influenza A viruses (IAVs) originating from animal reservoirs pose continuous threats to
human health as demonstrated by the Spanish flu pandemic. Infection starts by attachment …