The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

Abstract S100A8 and S100A9 are Ca 2+ binding proteins that belong to the S100 family.
Primarily expressed in neutrophils and monocytes, S100A8 and S100A9 play critical roles in …

Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of
the world. ESCC development presents a multistep pathogenic process from inflammation to …

Nutrient transition metals are required cofactors for many proteins to perform functions
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor
immune microenvironment (TIME) formed by interactions among cancer cells, immune cells …

Background The transforming growth factor‐β (TGF‐β) pathway plays a pivotal role in
inducing epithelial‐mesenchymal transition (EMT), which is a key step in cancer invasion …

Exosomes have recently emerged as key mediators of different physiological and
pathological processes. However, there has been few report about proteomic analysis of …

Approximately 90% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC).
PDAC is the fourth leading cause of cancer death world-wide. Therapies for PDAC are …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic cancer with
a poor prognosis and low survival rates. The prognostic and predictive biomarkers of PDAC …

Tumor-associated macrophages are associated with more malignant phenotypes of
esophageal squamous cell carcinoma (ESCC) cells. Previously, an indirect co-culture assay …