DNA methylation clocks and their predictive capacity for aging phenotypes and healthspan

T Bergsma, E Rogaeva - Neuroscience insights, 2020 - journals.sagepub.com
The number of age predictors based on DNA methylation (DNAm) profile is rising due to
their potential in predicting healthspan and application in age-related illnesses, such as …

Recent progress, methods and perspectives in forensic epigenetics

A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …

[HTML][HTML] DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing

A Vidaki, D Ballard, A Aliferi, TH Miller… - Forensic Science …, 2017 - Elsevier
The ability to estimate the age of the donor from recovered biological material at a crime
scene can be of substantial value in forensic investigations. Aging can be complex and is …

Developments in forensic DNA analysis

PR Haddrill - Emerging topics in life sciences, 2021 - portlandpress.com
The analysis of DNA from biological evidence recovered in the course of criminal
investigations can provide very powerful evidence when a recovered profile matches one …

[HTML][HTML] Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones

A Woźniak, A Heidegger, D Piniewska-Róg… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
DNA methylation is known as a biomarker for age with applications in forensics. Here we
describe the VISAGE (VISible Attributes through GEnomics) Consortium's enhanced tool for …

DNA methylation-based age prediction using massively parallel sequencing data and multiple machine learning models

A Aliferi, D Ballard, MD Gallidabino, H Thurtle… - Forensic Science …, 2018 - Elsevier
The field of DNA intelligence focuses on retrieving information from DNA evidence that can
help narrow down large groups of suspects or define target groups of interest. With recent …

[PDF][PDF] Forensic individual age estimation with DNA: from initial approaches to methylation tests

A Freire-Aradas, C Phillips… - Forensic Sci Rev, 2017 - forensicsciencereview.com
Individual age estimation is a key factor in forensic science analysis that can provide very
useful information applicable to criminal, legal, and anthropological investigations. Forensic …

Independent validation of DNA-based approaches for age prediction in blood

S Cho, SE Jung, SR Hong, EH Lee, JH Lee… - Forensic Science …, 2017 - Elsevier
Numerous molecular biomarkers have been proposed as predictors of chronological age.
Among them, T-cell specific DNA rearrangement and DNA methylation markers have been …

[HTML][HTML] Molecular basis of ageing in chronic metabolic diseases

R Spinelli, L Parrillo, M Longo, P Florese… - Journal of …, 2020 - Springer
Aim Over the last decades, the shift in age distribution towards older ages and the
progressive ageing which has occurred in most populations have been paralleled by a …

Age estimation with DNA: from forensic DNA fingerprinting to forensic (epi) genomics: a mini-review

W Parson - Gerontology, 2018 - karger.com
Forensic genetics developed from protein-based techniques a quarter of a century ago and
became famous as “DNA fingerprinting,” this being based on restriction fragment length …