Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?
K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …
research following several theoretical and clinical lines, all existing treatments for the …
Adenosine as a multi-signalling guardian angel in human diseases: when, where and how does it exert its protective effects?
The importance of adenosine for human health cannot be overstated. Indeed, this ubiquitous
nucleoside is an integral component of ATP, and regulates the function of every tissue and …
nucleoside is an integral component of ATP, and regulates the function of every tissue and …
Hypoxia induces immunosuppression, metastasis and drug resistance in pancreatic cancers
H Zhang, K Cao, J Xiang, M Zhang, M Zhu, Q Xi - Cancer Letters, 2023 - Elsevier
Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …
Redox regulation of inflammation: old elements, a new story
Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …
ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence
The Aspergillus fumigatus sterol regulatory element binding protein (SREBP) SrbA belongs
to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for …
to the basic Helix-Loop-Helix (bHLH) family of transcription factors and is crucial for …
The hypoxia-adenosine link during myocardial ischemia—reperfusion injury
Despite increasing availability and more successful interventional approaches to restore
coronary reperfusion, myocardial ischemia-reperfusion injury is a substantial cause of …
coronary reperfusion, myocardial ischemia-reperfusion injury is a substantial cause of …
[PDF][PDF] Definition of inflammation, causes of inflammation and possible anti-inflammatory strategies
SV Stankov - Open Inflamm J, 2012 - Citeseer
Current definition of inflammation by its cardinal signs is obsolete and unsuitable for guiding
adequate therapeutic strategies. Furthermore, present theory of the inflammatory process …
adequate therapeutic strategies. Furthermore, present theory of the inflammatory process …
Targeting hypoxia signaling for perioperative organ injury
January 2018• Volume 126• Number 1 www. anesthesia-analgesia. org 309 targeted
therapeutically in patients as a potential treatment approach for the prevention or treatment …
therapeutically in patients as a potential treatment approach for the prevention or treatment …
Short-term responses of the kidney to high altitude in mountain climbers
AS Goldfarb-Rumyantzev… - Nephrology Dialysis …, 2014 - academic.oup.com
In high-altitude climbers, the kidneys play a crucial role in acclimatization and in mountain
sickness syndromes [acute mountain sickness (AMS), high-altitude cerebral edema, high …
sickness syndromes [acute mountain sickness (AMS), high-altitude cerebral edema, high …
SARS-CoV-2 infection: host response, immunity, and therapeutic targets
P Shivshankar, H Karmouty-Quintana, T Mills… - Inflammation, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …