Hematopoietic stem cell approaches to cancer
Hematopoietic stem cells (HSCs) and progenitor cells are particularly attractive for gene
therapy. The ability to make all different kinds of blood cells for the life of a recipient is …
therapy. The ability to make all different kinds of blood cells for the life of a recipient is …
[HTML][HTML] Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapy
MS Nagree, L López-Vásquez… - World journal of stem …, 2015 - ncbi.nlm.nih.gov
With the advent of safer and more efficient gene transfer methods, gene therapy has become
a viable solution for many inherited and acquired disorders. Hematopoietic stem cells …
a viable solution for many inherited and acquired disorders. Hematopoietic stem cells …
211Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy
CR Burtner, D Chandrasekaran, EB Santos… - Human Gene …, 2015 - liebertpub.com
Most hematopoietic stem cell gene therapy studies require host conditioning to allow for
efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment …
efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment …
Inhibition of methotrexate induced toxicity in the adult rat spleen by adalimumab
Methotrexate (MTX) has been in use for the treatment of rheumatoid arthritis (RA), psoriasis,
and cancer since 1948. Its toxic side effects on tissues and organs have been well …
and cancer since 1948. Its toxic side effects on tissues and organs have been well …