Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

The unifying feature of all proteins that are transported out of the cytoplasm of gram-negative
bacteria by the general secretory pathway (GSP) is the presence of a long stretch of …

As the sole site of nucleocytoplasmic transport, the nuclear pore complex (NPC) has a vital
cellular role. Nonetheless, much remains to be learned about many fundamental aspects of …

Mitochondria import many hundreds of different proteins that are encoded by nuclear genes.
These proteins are targeted to the mitochondria, translocated through the mitochondrial …

Preprotein translocation in E. coli requires ATP, the membrane electrochemical potential
ASH+, and translacase, an enzyme with an ATPase domain (SecA) and the membrane …

The Ras-related nuclear protein, Ran, has been implicated in nuclear transport. By
screening a HeLa cell λ expression library with Ran-GTP and sequencing overlapping …

Nuclear pore complexes (NPCs) have been isolated from the yeast Saccharomyces.
Negative stain electron microscopy of the isolated NPCs and subsequent image …

Instability of the mitochondrial genome (mtDNA) is a general problem from yeasts to
humans. However, its genetic control is not well documented except in the yeast …

Ten mitochondrial carriers have been purified from animal mitochondria. They are small
proteins with a molecular mass ranging from 28 to 34 kDa on SDS‐PAGE. So far, five of …

We have purified peroxisomal membranes from Saccharomyces cerevisiae after induction of
peroxisomes in oleic acid-containing media. About 30 distinct proteins could be discerned …