Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review

MI Khan, MI Hossain, MK Hossain… - ACS Applied Bio …, 2022 - ACS Publications
Traditional treatment approaches for cancer involve intravenous chemotherapy or other
forms of drug delivery. These therapeutic measures suffer from several limitations such as …

STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity

EL Dane, A Belessiotis-Richards, C Backlund… - Nature Materials, 2022 - nature.com
Activation of the innate immune STimulator of INterferon Genes (STING) pathway potentiates
antitumour immunity, but systemic delivery of STING agonists to tumours is challenging. We …

Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment

Z Li, Y Ding, J Liu, J Wang, F Mo, Y Wang… - Nature …, 2022 - nature.com
Immunosuppressive cells residing in the tumor microenvironment, especially tumor
associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the …

Strategies to improve the EPR effect: A mechanistic perspective and clinical translation

M Ikeda-Imafuku, LLW Wang, D Rodrigues… - Journal of Controlled …, 2022 - Elsevier
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …

[HTML][HTML] Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and …

Y Lu, Q Luo, X Jia, JP Tam, H Yang, Y Shen… - Journal of Pharmaceutical …, 2023 - Elsevier
Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …

[HTML][HTML] Dyes adsorption from aqueous media through the nanotechnology: A review

C Osagie, A Othmani, S Ghosh, A Malloum… - Journal of Materials …, 2021 - Elsevier
The article aims to review the research findings on the adsorption of dyes from aqueous
media. It was observed from the review that activated carbon and Polymer based …

Molecular engineering to boost AIE‐active free radical photogenerators and enable high‐performance photodynamic therapy under hypoxia

Q Wan, R Zhang, Z Zhuang, Y Li… - Advanced Functional …, 2020 - Wiley Online Library
The severe hypoxia in solid tumors and the vicious aggregation‐caused fluorescence
quenching (ACQ) of conventional photosensitizers (PSs) have limited the application of …

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …