Hepatocellular carcinoma (HCC) is among the most lethal and prevalent cancers in the
human population. Different etiological factors such as hepatitis B and C virus, alcohol and …

Leptin, the first described adipokine, interplays with hepatic metabolism. The aim of this
review was to summarize available data on the association between leptin and nonalcoholic …

Non-alcoholic fatty liver disease (NAFLD), which affects about a quarter of the global
population, poses a substantial health and economic burden in all countries, yet there is no …

Liver cirrhosis is frequently accompanied by disease-related malnutrition (DRM) and
sarcopenia, defined as loss of skeletal muscle mass and function. DRM and sarcopenia …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

A breakthrough using “reverse pharmacology” identified and characterized acyl ghrelin from
the stomach as the endogenous cognate ligand for the growth hormone (GH) secretagogue …

Background Hepatocellular carcinoma (HCC) is associated with inflammation, and roughly
30% of the global population shows serological evidence of current or past infection with …

The cytokine-mediated suppression of hepatic drug-metabolizing enzymes by inflammatory
disease and the relief of this suppression by successful disease treatment have recently …

Abstract Increased interleukin‐6 (IL‐6) production is implicated in the pathogenesis of
hepatocellular carcinoma (HCC) in animal models. Although previous studies showed that …

Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-
Pugh score and the model of end-stage liver disease score have been established to assess …